The evidence is mounting against aspirin for use in those without coronary artery disease:
Aspirin is ineffective for primary prevention of cardiovascular events even in high-risk diabetics, researchers found.
Among patients with diabetes and asymptomatic peripheral arterial disease, aspirin did not reduce primary fatal and non-fatal cardiovascular events compared with placebo.
The use of aspirin is appealing because it is inexpensive, and has shown benefit in those who had already suffered a heart attack or stroke.
Six other well-controlled studies also found similar results, and which is enough to convince internist Robert Centor.
