Skip to content
  • About
  • Contact
  • Contribute
  • Book
  • Careers
  • Podcast
  • Recommended
  • Speaking
KevinMD
  • All
  • Physician
  • Practice
  • Policy
  • Finance
  • Conditions
  • .edu
  • Patient
  • Meds
  • Tech
  • Social
  • Video
  • All
  • Physician
  • Practice
  • Policy
  • Finance
  • Conditions
  • .edu
  • Patient
  • Meds
  • Tech
  • Social
  • Video
    • All
    • Physician
    • Practice
    • Policy
    • Finance
    • Conditions
    • .edu
    • Patient
    • Meds
    • Tech
    • Social
    • Video
    • About
    • Contact
    • Contribute
    • Book
    • Careers
    • Podcast
    • Recommended
    • Speaking
KevinMD
  • All
  • Physician
  • Practice
  • Policy
  • Finance
  • Conditions
  • .edu
  • Patient
  • Meds
  • Tech
  • Social
  • Video
    • All
    • Physician
    • Practice
    • Policy
    • Finance
    • Conditions
    • .edu
    • Patient
    • Meds
    • Tech
    • Social
    • Video
    • About
    • Contact
    • Contribute
    • Book
    • Careers
    • Podcast
    • Recommended
    • Speaking
  • About KevinMD | Kevin Pho, MD
  • Be heard on social media’s leading physician voice
  • Contact Kevin
  • Discounted enhanced author page
  • DMCA Policy
  • Establishing, Managing, and Protecting Your Online Reputation: A Social Media Guide for Physicians and Medical Practices
  • Group vs. individual disability insurance for doctors: pros and cons
  • KevinMD influencer opportunities
  • Opinion and commentary by KevinMD
  • Physician burnout speakers to keynote your conference
  • Physician Coaching by KevinMD
  • Physician keynote speaker: Kevin Pho, MD
  • Physician Speaking by KevinMD: a boutique speakers bureau
  • Primary care physician in Nashua, NH | Kevin Pho, MD
  • Privacy Policy
  • Recommended services by KevinMD
  • Terms of Use Agreement
  • Thank you for subscribing to KevinMD
  • Thank you for upgrading to the KevinMD enhanced author page
  • The biggest mistake doctors make when purchasing disability insurance
  • The doctor’s guide to disability insurance: short-term vs. long-term
  • The KevinMD ToolKit
  • Upgrade to the KevinMD enhanced author page
  • Why own-occupation disability insurance is a must for doctors

Why you should never order a herpes IgM blood test

Jennifer Gunter, MD
Conditions
July 27, 2013
Share
Tweet
Share

Routine screening blood tests for herpes are not recommended by the Centers for Disease Control. When I say routine screening I mean a scenario such as, “I want to get checked for everything, ok?”

Blood tests for herpes do have a place in specific clinical situations, but that’s for another post.

But say you did get a herpes blood test (even though it’s not recommended many people seem to get it done) and it’s positive for something called IgM antibodies. Armed with these results your doctor proceeds to tell you that these results mean you caught herpes recently, so you start to freak out.

Stop right there.

A positive herpes IgM test means nothing. I’ve posted about this before but enough people continue to leave comments on my herpes posts asking about their positive IgM test that it bears repeating.

A herpes IgM test is never, ever, ever indicated. Not ever, because it doesn’t mean much of anything.

“Impossible,” you say. “My doctor ordered it, so it must be a valid test.”

Well, no.

Let’s review antibodies. When we are exposed to infections we make antibodies. Antibodies are proteins produced by the immune system that fight bacteria and viruses, hopefully containing these infections. IgM antibodies are made first, within weeks, but they don’t hang around. Think of them as first responders. IgG antibodies take longer to produce, but once present you typically have them for life.

However, with herpes this response system is a little different. The herpes virus is never cleared by the immune system. Once you stop shedding the virus it takes up shop in the nerves (the dorsal root ganglia to be specific). From time to time the virus is reactivated, either producing ulcers or just asymptomatic shedding of the virus. How often the virus is reactivated and how much virus is shed depends on many factors.

It is this ability to stay dormant and then reactivate that is a defining characteristic of herpes viruses, but this also affects IgM production. When herpes is reactivated, even though it is not a brand new infection, the body often produces IgM. So, the presence of IgM antibodies against herpes don’t tell you if this is a recent infection or a reactivation and so is of no use clinically. In addition, the IgM tests offered by commercial labs have not been well vetted as type specific, meaning they may not reliably distinguish between IgM for herpes type 1 and type 2 (and remember, by the age of 30 almost everyone is positive for heroes type 1).

Just because a lab offers a test doesn’t mean that the test is useful for your medical care or reliable.

Despite this, many people get tested for herpes IgM.

If you are getting a blood test for herpes, ask your doctor specifically what test that means. If your doctor is ordering an IgM test then go somewhere else, because it means they don’t know enough about herpes to be testing you in the first place.

Disclaimer:  This post is not direct medical advice.

Jennifer Gunter is an obstetrician-gynecologist and author of The Preemie Primer. She blogs at her self-titled site, Dr. Jen Gunter.

Prev

A watershed moment in my lifetime of treating cancer patients

July 26, 2013 Kevin 1
…
Next

Haunted by an autism diagnosis: A sense of closure after 20 years

July 27, 2013 Kevin 1
…

Tagged as: Infectious Disease

< Previous Post
A watershed moment in my lifetime of treating cancer patients
Next Post >
Haunted by an autism diagnosis: A sense of closure after 20 years

ADVERTISEMENT

More by Jennifer Gunter, MD

  • The Ellen Show broadcasts potentially harmful information about ovarian cancer screening

    Jennifer Gunter, MD
  • Dear science: an appreciation

    Jennifer Gunter, MD
  • Are there too many female OB/GYNs?

    Jennifer Gunter, MD

More in Conditions

  • Postpartum lactation support is a health care gap

    Maddie Beans
  • CDC opioid guidelines are harming chronic pain patients

    Frank Carroll
  • School nursing for medically complex kids is not guaranteed

    Ashley Youngdale
  • Communication access is a patient safety issue

    Chris Ross, PhD, CCC-SLP
  • Psychedelics and neuroplasticity are rewiring the brain

    Marc Arginteanu, MD
  • The balloon catheter bleeding risk no one talks about

    Deanna Vargo, RN, Nish Chasmawala, and Simone Hugar
  • Most Popular

  • Past Week

    • Polycystic ovary syndrome is more than ovarian

      Oluyemisi Famuyiwa, MD | Conditions
    • Metrics got you into medicine and are making you unhappy in it [PODCAST]

      The Podcast by KevinMD | Podcast
    • Wearable technology saves lives through early detection

      Sidney J. Winawer, MD | Conditions
    • Social media told her to abort her Turner syndrome baby

      Stephanie Waggel, MD | Conditions
    • Why medical training ignores the business of medicine

      Santoshi Billakota, MD | Physician
    • The residency personal statement is an identity problem

      Kathleen Muldoon, PhD | Education
  • Past 6 Months

    • I Googled my own name and a corporate clinic I’ve never worked at appeared [PODCAST]

      The Podcast by KevinMD | Podcast
    • Primary care crisis requires new training and skills

      Justin Oldfield, MD | Physician
    • Polycystic ovary syndrome is more than ovarian

      Oluyemisi Famuyiwa, MD | Conditions
    • Why nursing home regulations must address mental illness

      Amanda M. Buster and J. Wesley Boyd, MD, PhD | Conditions
    • The cost of chaos in medical malpractice litigation

      Howard Smith, MD | Physician
    • Why artificial intelligence displacement threatens medical specialties

      H. Michael Boulton, MD | Physician
  • Recent Posts

    • A nurse in the Holocaust meets an impossible order

      Dr. Jonathan Hammel | Physician
    • Postpartum lactation support is a health care gap

      Maddie Beans | Conditions
    • Metrics got you into medicine and are making you unhappy in it [PODCAST]

      The Podcast by KevinMD | Podcast
    • CDC opioid guidelines are harming chronic pain patients

      Frank Carroll | Conditions
    • Psychiatry and human suffering are not always the same

      Devina Maya Wadhwa, MD | Physician
    • Can peer review in academia survive faculty overload?

      Rao M. Uppu, PhD | Education

Subscribe to KevinMD and never miss a story!

Get free updates delivered free to your inbox.


Find jobs at
Careers by KevinMD.com

Search thousands of physician, PA, NP, and CRNA jobs now.

Learn more

View 4 Comments >

Founded in 2004 by Kevin Pho, MD, KevinMD.com is the web’s leading platform where physicians, advanced practitioners, nurses, medical students, and patients share their insight and tell their stories.

Social

  • Like on Facebook
  • Follow on Twitter
  • Connect on Linkedin
  • Subscribe on Youtube
  • Instagram

ADVERTISEMENT

  • Most Popular

  • Past Week

    • Polycystic ovary syndrome is more than ovarian

      Oluyemisi Famuyiwa, MD | Conditions
    • Metrics got you into medicine and are making you unhappy in it [PODCAST]

      The Podcast by KevinMD | Podcast
    • Wearable technology saves lives through early detection

      Sidney J. Winawer, MD | Conditions
    • Social media told her to abort her Turner syndrome baby

      Stephanie Waggel, MD | Conditions
    • Why medical training ignores the business of medicine

      Santoshi Billakota, MD | Physician
    • The residency personal statement is an identity problem

      Kathleen Muldoon, PhD | Education
  • Past 6 Months

    • I Googled my own name and a corporate clinic I’ve never worked at appeared [PODCAST]

      The Podcast by KevinMD | Podcast
    • Primary care crisis requires new training and skills

      Justin Oldfield, MD | Physician
    • Polycystic ovary syndrome is more than ovarian

      Oluyemisi Famuyiwa, MD | Conditions
    • Why nursing home regulations must address mental illness

      Amanda M. Buster and J. Wesley Boyd, MD, PhD | Conditions
    • The cost of chaos in medical malpractice litigation

      Howard Smith, MD | Physician
    • Why artificial intelligence displacement threatens medical specialties

      H. Michael Boulton, MD | Physician
  • Recent Posts

    • A nurse in the Holocaust meets an impossible order

      Dr. Jonathan Hammel | Physician
    • Postpartum lactation support is a health care gap

      Maddie Beans | Conditions
    • Metrics got you into medicine and are making you unhappy in it [PODCAST]

      The Podcast by KevinMD | Podcast
    • CDC opioid guidelines are harming chronic pain patients

      Frank Carroll | Conditions
    • Psychiatry and human suffering are not always the same

      Devina Maya Wadhwa, MD | Physician
    • Can peer review in academia survive faculty overload?

      Rao M. Uppu, PhD | Education

MedPage Today Professional

An Everyday Health Property Medpage Today

Copyright © 2026 KevinMD.com | Powered by Astra WordPress Theme

  • Terms of Use | Disclaimer
  • Privacy Policy
  • DMCA Policy
All Content © KevinMD, LLC
Site by Outthink Group

Why you should never order a herpes IgM blood test
4 comments

Comments are moderated before they are published. Please read the comment policy.

Loading Comments...