Skip to content
  • About
  • Contact
  • Contribute
  • Book
  • Careers
  • Podcast
  • Recommended
  • Speaking
  • All
  • Physician
  • Practice
  • Policy
  • Finance
  • Conditions
  • .edu
  • Patient
  • Meds
  • Tech
  • Social
  • Video
    • All
    • Physician
    • Practice
    • Policy
    • Finance
    • Conditions
    • .edu
    • Patient
    • Meds
    • Tech
    • Social
    • Video
    • About
    • Contact
    • Contribute
    • Book
    • Careers
    • Podcast
    • Recommended
    • Speaking

Why you should never order a herpes IgM blood test

Jennifer Gunter, MD
Conditions
July 27, 2013
Share
Tweet
Share

Routine screening blood tests for herpes are not recommended by the Centers for Disease Control. When I say routine screening I mean a scenario such as, “I want to get checked for everything, ok?”

Blood tests for herpes do have a place in specific clinical situations, but that’s for another post.

But say you did get a herpes blood test (even though it’s not recommended many people seem to get it done) and it’s positive for something called IgM antibodies. Armed with these results your doctor proceeds to tell you that these results mean you caught herpes recently, so you start to freak out.

Stop right there.

A positive herpes IgM test means nothing. I’ve posted about this before but enough people continue to leave comments on my herpes posts asking about their positive IgM test that it bears repeating.

A herpes IgM test is never, ever, ever indicated. Not ever, because it doesn’t mean much of anything.

“Impossible,” you say. “My doctor ordered it, so it must be a valid test.”

Well, no.

Let’s review antibodies. When we are exposed to infections we make antibodies. Antibodies are proteins produced by the immune system that fight bacteria and viruses, hopefully containing these infections. IgM antibodies are made first, within weeks, but they don’t hang around. Think of them as first responders. IgG antibodies take longer to produce, but once present you typically have them for life.

However, with herpes this response system is a little different. The herpes virus is never cleared by the immune system. Once you stop shedding the virus it takes up shop in the nerves (the dorsal root ganglia to be specific). From time to time the virus is reactivated, either producing ulcers or just asymptomatic shedding of the virus. How often the virus is reactivated and how much virus is shed depends on many factors.

It is this ability to stay dormant and then reactivate that is a defining characteristic of herpes viruses, but this also affects IgM production. When herpes is reactivated, even though it is not a brand new infection, the body often produces IgM. So, the presence of IgM antibodies against herpes don’t tell you if this is a recent infection or a reactivation and so is of no use clinically. In addition, the IgM tests offered by commercial labs have not been well vetted as type specific, meaning they may not reliably distinguish between IgM for herpes type 1 and type 2 (and remember, by the age of 30 almost everyone is positive for heroes type 1).

Just because a lab offers a test doesn’t mean that the test is useful for your medical care or reliable.

Despite this, many people get tested for herpes IgM.

If you are getting a blood test for herpes, ask your doctor specifically what test that means. If your doctor is ordering an IgM test then go somewhere else, because it means they don’t know enough about herpes to be testing you in the first place.

Disclaimer:  This post is not direct medical advice.

ADVERTISEMENT

Jennifer Gunter is an obstetrician-gynecologist and author of The Preemie Primer. She blogs at her self-titled site, Dr. Jen Gunter.

Prev

A watershed moment in my lifetime of treating cancer patients

July 26, 2013 Kevin 1
…
Next

Haunted by an autism diagnosis: A sense of closure after 20 years

July 27, 2013 Kevin 1
…

Tagged as: Infectious Disease

Post navigation

< Previous Post
A watershed moment in my lifetime of treating cancer patients
Next Post >
Haunted by an autism diagnosis: A sense of closure after 20 years

ADVERTISEMENT

ADVERTISEMENT

ADVERTISEMENT

More by Jennifer Gunter, MD

  • The Ellen Show broadcasts potentially harmful information about ovarian cancer screening

    Jennifer Gunter, MD
  • Dear science: an appreciation

    Jennifer Gunter, MD
  • Are there too many female OB/GYNs?

    Jennifer Gunter, MD

More in Conditions

  • Make cognitive testing as routine as a blood pressure check

    Joshua Baker and James Jackson, PsyD
  • Reimagining diabetes care with nutrition, not prescriptions

    William Hsu, MD
  • A speech pathologist’s key to better, safer patient care

    Adena Dacy, CCC-SLP
  • How collaboration saved my life from a rare disease doctors couldn’t diagnose

    Tami Burdick
  • Why your emotions are your greatest compass in therapy and life

    Maire Daugharty, MD
  • Patients are not waiting: What MCDA twin parents teach us about shared decision-making

    Stephanie Ernst
  • Most Popular

  • Past Week

    • What’s driving medical students away from primary care?

      ​​Vineeth Amba, MPH, Archita Goyal, and Wayne Altman, MD | Education
    • A faster path to becoming a doctor is possible—here’s how

      Ankit Jain | Education
    • A world without antidepressants: What could possibly go wrong?

      Tomi Mitchell, MD | Meds
    • Make cognitive testing as routine as a blood pressure check

      Joshua Baker and James Jackson, PsyD | Conditions
    • Rethinking patient payments: Why billing is the new frontline of patient care [PODCAST]

      The Podcast by KevinMD | Podcast
    • Why the words doctors use matter more than they think

      Erin Paterson | Conditions
  • Past 6 Months

    • What’s driving medical students away from primary care?

      ​​Vineeth Amba, MPH, Archita Goyal, and Wayne Altman, MD | Education
    • Internal Medicine 2025: inspiration at the annual meeting

      American College of Physicians | Physician
    • The silent crisis hurting pain patients and their doctors

      Kayvan Haddadan, MD | Physician
    • What happened to real care in health care?

      Christopher H. Foster, PhD, MPA | Policy
    • How the CDC’s opioid rules created a crisis for chronic pain patients

      Charles LeBaron, MD | Conditions
    • Are quotas a solution to physician shortages?

      Jacob Murphy | Education
  • Recent Posts

    • Rethinking patient payments: Why billing is the new frontline of patient care [PODCAST]

      The Podcast by KevinMD | Podcast
    • The dreaded question: Do you have boys or girls?

      Pamela Adelstein, MD | Physician
    • Make cognitive testing as routine as a blood pressure check

      Joshua Baker and James Jackson, PsyD | Conditions
    • Reimagining diabetes care with nutrition, not prescriptions

      William Hsu, MD | Conditions
    • Why funding cuts to academic medical centers impact all of us [PODCAST]

      The Podcast by KevinMD | Podcast
    • What’s driving medical students away from primary care?

      ​​Vineeth Amba, MPH, Archita Goyal, and Wayne Altman, MD | Education

Subscribe to KevinMD and never miss a story!

Get free updates delivered free to your inbox.


Find jobs at
Careers by KevinMD.com

Search thousands of physician, PA, NP, and CRNA jobs now.

Learn more

View 4 Comments >

Founded in 2004 by Kevin Pho, MD, KevinMD.com is the web’s leading platform where physicians, advanced practitioners, nurses, medical students, and patients share their insight and tell their stories.

Social

  • Like on Facebook
  • Follow on Twitter
  • Connect on Linkedin
  • Subscribe on Youtube
  • Instagram

ADVERTISEMENT

ADVERTISEMENT

ADVERTISEMENT

ADVERTISEMENT

  • Most Popular

  • Past Week

    • What’s driving medical students away from primary care?

      ​​Vineeth Amba, MPH, Archita Goyal, and Wayne Altman, MD | Education
    • A faster path to becoming a doctor is possible—here’s how

      Ankit Jain | Education
    • A world without antidepressants: What could possibly go wrong?

      Tomi Mitchell, MD | Meds
    • Make cognitive testing as routine as a blood pressure check

      Joshua Baker and James Jackson, PsyD | Conditions
    • Rethinking patient payments: Why billing is the new frontline of patient care [PODCAST]

      The Podcast by KevinMD | Podcast
    • Why the words doctors use matter more than they think

      Erin Paterson | Conditions
  • Past 6 Months

    • What’s driving medical students away from primary care?

      ​​Vineeth Amba, MPH, Archita Goyal, and Wayne Altman, MD | Education
    • Internal Medicine 2025: inspiration at the annual meeting

      American College of Physicians | Physician
    • The silent crisis hurting pain patients and their doctors

      Kayvan Haddadan, MD | Physician
    • What happened to real care in health care?

      Christopher H. Foster, PhD, MPA | Policy
    • How the CDC’s opioid rules created a crisis for chronic pain patients

      Charles LeBaron, MD | Conditions
    • Are quotas a solution to physician shortages?

      Jacob Murphy | Education
  • Recent Posts

    • Rethinking patient payments: Why billing is the new frontline of patient care [PODCAST]

      The Podcast by KevinMD | Podcast
    • The dreaded question: Do you have boys or girls?

      Pamela Adelstein, MD | Physician
    • Make cognitive testing as routine as a blood pressure check

      Joshua Baker and James Jackson, PsyD | Conditions
    • Reimagining diabetes care with nutrition, not prescriptions

      William Hsu, MD | Conditions
    • Why funding cuts to academic medical centers impact all of us [PODCAST]

      The Podcast by KevinMD | Podcast
    • What’s driving medical students away from primary care?

      ​​Vineeth Amba, MPH, Archita Goyal, and Wayne Altman, MD | Education

MedPage Today Professional

An Everyday Health Property Medpage Today
  • Terms of Use | Disclaimer
  • Privacy Policy
  • DMCA Policy
All Content © KevinMD, LLC
Site by Outthink Group

Why you should never order a herpes IgM blood test
4 comments

Comments are moderated before they are published. Please read the comment policy.

Loading Comments...