Skip to content
  • About
  • Contact
  • Contribute
  • Book
  • Careers
  • Podcast
  • Recommended
  • Speaking
  • All
  • Physician
  • Practice
  • Policy
  • Finance
  • Conditions
  • .edu
  • Patient
  • Meds
  • Tech
  • Social
  • Video
    • All
    • Physician
    • Practice
    • Policy
    • Finance
    • Conditions
    • .edu
    • Patient
    • Meds
    • Tech
    • Social
    • Video
    • About
    • Contact
    • Contribute
    • Book
    • Careers
    • Podcast
    • Recommended
    • Speaking

Drug prices and fast approvals can harm patients

Martha Rosenberg
Meds
November 23, 2023
Share
Tweet
Share

An excerpt from Big Food, Big Pharma, Big Lies.

Few fail to be shocked at the rising prices of some prescription drugs. “Drug companies have raised prices relentlessly for decades while manipulating the patent system and other laws to delay competition from lower-priced generics,” reported the House Committee on Oversight and Reform in December 2021.

The price of insulin rose by 54 percent between 2014 to 2019, and the anti-parasitic drug Daraprim was repriced from $13.50 to $750 in 2015 by Turing Pharmaceuticals founder Martin Shkreli. Mylan raised the price of EpiPen to $600 from $100 with no warning.

And then there were the hepatitis C drugs which cured the condition for the first time. Gilead Science priced Sovaldi, one of the first such hepatitis C drugs, at a shocking $1,000 a pill or $84,000 for a course of treatment. Lawmakers worried that the opportunistic prices would sack entitlement programs, and they did;  in 2014 alone, Medicare and Medicaid spent over $5 billion on Sovaldi and Gilead’s follow-up hepatitis C drug, Harvoni.

In 2017, Harvoni ad campaigns on TV, in broadcast, and on posters along train commuter lines unabashedly stressed screening, warning people that if they were born between 1945 and 1965, they could have hepatitis C and not know it.

The shift to scare tactics and a push for screening—sometimes called disease mongering— was not a coincidence. According to the pharmaceutical trade website Fierce Pharma, Gilead’s hepatitis blockbusters at the time were “in freefall, and its pool of eligible patients has shrunk dramatically thanks to the success of its meds.” If “all baby boomers got tested for the virus, though? That could help stem the tide—and it’s exactly the move the company is recommending with its latest awareness push,” continued the site.

Some of the ads for hepatitis C drugs included the Centers for Disease Control and Prevention (CDC) logo which instantly increased marketing credibility but also raised questions about Gilead donations to the CDC foundation and quid pro quos. Few realize that the CDC foundation boasts many drugmaker donors like Abbott, AbbVie, Bayer, AstraZeneca, Merck, Pfizer, GlaxoSmithKline Biologicals, Eli Lilly, Amgen, Genentech and, as we noted, Gilead which raises questions about monetary conflicts of interest.

And, when it came to hepatitis C drugs, “there was more,” as the infomercials say. The drugs had been rushed to market so quickly, the their penchant for reactivating pre-existing hepatitis B was completely overlooked and add post hoc warnings had to be added to the label by 2016.

In 2017, the New York Times reported additional, undisclosed risks with the hepatitis C drugs. Of  250,000 patients treated with them, 524 experienced liver failure and 165 died wrote the newspaper. “An additional 1,058 had severe liver injury, and in 761 the drugs appeared not to work.”

Thomas J. Moore, a senior scientist at the Institute for Safe Medication Practices, echoed what many were thinking as the hepatitis drug risks unfolded: does the rush to bring a new drug treatment to market come at an unforeseen cost to patient safety? Were they approved too quickly? Clearly, fast approvals, like ever-increasing drug prices, can and do harm patients.

Martha Rosenberg is a health reporter and the author of Big Food, Big Pharma, Big Lies and Born With a Junk Food Deficiency.  

Prev

Job stacking for doctors: a modern approach to work-life balance

November 23, 2023 Kevin 0
…
Next

Navigating life stories and medical decisions

November 24, 2023 Kevin 0
…

Tagged as: Medications

Post navigation

< Previous Post
Job stacking for doctors: a modern approach to work-life balance
Next Post >
Navigating life stories and medical decisions

ADVERTISEMENT

More by Martha Rosenberg

  • How drugmakers manipulate your health from diagnosis to prescription

    Martha Rosenberg
  • Conflicts of interest are eroding trust in U.S. health agencies

    Martha Rosenberg
  • How drug companies turned “depression” into a billion-dollar industry

    Martha Rosenberg

Related Posts

  • Why social media may be causing real emotional harm

    Edwin Leap, MD
  • Patients alone cannot combat high health care prices

    Peter Ubel, MD
  • Why is the government so scared of directly negotiating drug prices?

    Robert Laszewski
  • Negotiating lower drug prices in America: The tradeoffs are worth it.

    Konye Ori
  • Beyond the EpiPen: Irrational drug prices are now pervasive

    Stephen C. Schimpff, MD
  • How drug prices are manipulated

    Steven Reidbord, MD

More in Meds

  • How drugmakers manipulate your health from diagnosis to prescription

    Martha Rosenberg
  • The food-drug interaction risks your doctor may be missing

    Frank Jumbe
  • Why retail pharmacies are the future of diverse clinical trials

    Shelli Pavone
  • Why does rifaximin cost 95 percent more in the U.S. than in Asia?

    Jai Kumar, MD, Brian Nohomovich, DO, PhD and Leonid Shamban, DO
  • A world without antidepressants: What could possibly go wrong?

    Tomi Mitchell, MD
  • The truth about GLP-1 medications for weight loss: What every patient should know

    Nisha Kuruvadi, DO
  • Most Popular

  • Past Week

    • Why are medical students turning away from primary care? [PODCAST]

      The Podcast by KevinMD | Podcast
    • Here’s what providers really need in a modern EHR

      Laura Kohlhagen, MD, MBA | Tech
    • Why “do no harm” might be harming modern medicine

      Sabooh S. Mubbashar, MD | Physician
    • Why doctors are reclaiming control from burnout culture

      Maureen Gibbons, MD | Physician
    • How community paramedicine impacts Indigenous elders

      Noah Weinberg | Conditions
    • A physician’s reflection on love, loss, and finding meaning in grief [PODCAST]

      The Podcast by KevinMD | Podcast
  • Past 6 Months

    • Why are medical students turning away from primary care? [PODCAST]

      The Podcast by KevinMD | Podcast
    • Why tracking cognitive load could save doctors and patients

      Hiba Fatima Hamid | Education
    • Why “do no harm” might be harming modern medicine

      Sabooh S. Mubbashar, MD | Physician
    • Here’s what providers really need in a modern EHR

      Laura Kohlhagen, MD, MBA | Tech
    • What the world must learn from the life and death of Hind Rajab

      Saba Qaiser, RN | Conditions
    • How medical culture hides burnout in plain sight

      Marco Benítez | Conditions
  • Recent Posts

    • A physician’s reflection on love, loss, and finding meaning in grief [PODCAST]

      The Podcast by KevinMD | Podcast
    • How fragmented records and poor tracking degrade patient outcomes

      Michael R. McGuire | Policy
    • How New Mexico became a malpractice lawsuit hotspot

      Patrick Hudson, MD | Physician
    • How I learned to stop worrying and love AI

      Rajeev Dutta | Education
    • Understanding depression beyond biology: the power of therapy and meaning

      Maire Daugharty, MD | Conditions
    • Why compassion—not credentials—defines great doctors

      Dr. Saad S. Alshohaib | Physician

Subscribe to KevinMD and never miss a story!

Get free updates delivered free to your inbox.


Find jobs at
Careers by KevinMD.com

Search thousands of physician, PA, NP, and CRNA jobs now.

Learn more

Leave a Comment

Founded in 2004 by Kevin Pho, MD, KevinMD.com is the web’s leading platform where physicians, advanced practitioners, nurses, medical students, and patients share their insight and tell their stories.

Social

  • Like on Facebook
  • Follow on Twitter
  • Connect on Linkedin
  • Subscribe on Youtube
  • Instagram

ADVERTISEMENT

  • Most Popular

  • Past Week

    • Why are medical students turning away from primary care? [PODCAST]

      The Podcast by KevinMD | Podcast
    • Here’s what providers really need in a modern EHR

      Laura Kohlhagen, MD, MBA | Tech
    • Why “do no harm” might be harming modern medicine

      Sabooh S. Mubbashar, MD | Physician
    • Why doctors are reclaiming control from burnout culture

      Maureen Gibbons, MD | Physician
    • How community paramedicine impacts Indigenous elders

      Noah Weinberg | Conditions
    • A physician’s reflection on love, loss, and finding meaning in grief [PODCAST]

      The Podcast by KevinMD | Podcast
  • Past 6 Months

    • Why are medical students turning away from primary care? [PODCAST]

      The Podcast by KevinMD | Podcast
    • Why tracking cognitive load could save doctors and patients

      Hiba Fatima Hamid | Education
    • Why “do no harm” might be harming modern medicine

      Sabooh S. Mubbashar, MD | Physician
    • Here’s what providers really need in a modern EHR

      Laura Kohlhagen, MD, MBA | Tech
    • What the world must learn from the life and death of Hind Rajab

      Saba Qaiser, RN | Conditions
    • How medical culture hides burnout in plain sight

      Marco Benítez | Conditions
  • Recent Posts

    • A physician’s reflection on love, loss, and finding meaning in grief [PODCAST]

      The Podcast by KevinMD | Podcast
    • How fragmented records and poor tracking degrade patient outcomes

      Michael R. McGuire | Policy
    • How New Mexico became a malpractice lawsuit hotspot

      Patrick Hudson, MD | Physician
    • How I learned to stop worrying and love AI

      Rajeev Dutta | Education
    • Understanding depression beyond biology: the power of therapy and meaning

      Maire Daugharty, MD | Conditions
    • Why compassion—not credentials—defines great doctors

      Dr. Saad S. Alshohaib | Physician

MedPage Today Professional

An Everyday Health Property Medpage Today
  • Terms of Use | Disclaimer
  • Privacy Policy
  • DMCA Policy
All Content © KevinMD, LLC
Site by Outthink Group

Leave a Comment

Comments are moderated before they are published. Please read the comment policy.

Loading Comments...