I want to draw your attention to two fairly recent studies. One of these is the BIND study. I love it when studies use easy-to-remember acronyms because it really helps to keep them straight. The BIND study found that “Many prolonged symptoms subsequent to benzodiazepine use and discontinuation … have been shown in a large survey of benzodiazepine users. Benzodiazepine-induced neurological dysfunction (BIND) has been proposed as a term …
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The universe can be a very confusing place.
Quite often, things will happen together or one-after-another that will cause even learned people to connect two events as causative when they are not. These misattributions are not just of academic concern. They can have real-world consequences.
In 1347, a plague began to sweep through Europe. At the time, no one knew what caused plagues, and the germ theory of disease was centuries away. …
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Reports sent back to Washington during the Vietnam War made it clear to everyone. The U.S. was winning. There could be no debate or doubt. It was right there in the numbers. When searching for a metric to measure “success,” U.S. politicians and the military had come to rely on body count comparisons. Defining “winning” as having a higher body count. And by that measure, the U.S. was indeed winning. …
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In 2017, Attorney General Jeff Sessions became convinced that the opioid crisis was not the fault of cartels smuggling fentanyl across porous American checkpoints. And it wasn’t due to pharmaceutical companies corrupting drug approval officials and DEA administrators by hiring them as consultants after making decisions in the company’s favor. No. The opioid crisis was caused by American physicians coddling pain patients and addicts.
But reviewing all the actions of tens …
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The German pharmaceutical company Grunenthal has announced the start of a human addiction potential (HAP) trial of a first-in-class analgesic called cebranopadol, described as “less addictive” than previous medications. We’ve been down this road before.
This medication is both a mu-opioid peptide and nociptin/orphanin FQ peptide (NOP) receptor agonist. I must confess I had to look up the last one. NOP receptors are a type of kappa-type 3 opioid receptor coded …
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A recent article in the Macomb Daily reported that a “Shelby Township doctor was convicted last Thursday of all counts for conspiring to distribute more than 300,000 opioid prescription pills valued at over $6 million, following a trial in U.S. District Court in Ann Arbor, according to federal authorities.”
This sounds very serious on its face. But without context, the public, and even we, have no idea what this means. …
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In 1999, Sally Clark was convicted of murder. Her son, Christopher, had been born in September of 1996 and by all accounts, had been a healthy baby. Just three months later, an ambulance was called to the home, and the baby was dead.
The mother, Sally, said that she had just put him to bed and found him unresponsive not long after. The police were suspicious; she seemed a little cold …
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When I started medical school thirty years ago, and learned about the discovery of streptomycin, I wondered what it must have been like for the doctors who first used it to cure the “white death.” How satisfying it must have been to tell a previously hopeless patient, “We can cure you.”
What brought this to mind was my rotation at an old part of the hospital where I was training. I …
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First, it’s essential to understand that your prosecution doesn’t define you as a person. Most likely, the DEA never bothered to speak with you before deciding to arrest and prosecute you. Even if they did, the decision to prosecute you had been made long before any conversation took place. Your prosecution is the result of a long and strategic process, one in which the very notions of truth and justice …
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The sciences and even medicine have long been used to justify atrocities. In the early 1800s, the United States of America was a slave nation. Citizens were allowed to purchase and imprison other races and hold them in bondage as property. This is different from indentured servitude, where someone is held in bondage until they pay off a debt. The indentured servant still has some rights and autonomy; the slave …
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New Zealand just rescinded its ban on tobacco smoking at the same time that Donald Trump just suggested the death penalty could cure the drug problem. What did New Zealand learn? And how has drug prohibition worked out in the past?
In 1511, the governor of Mecca, Khair Beg, had a serious problem. A powerful stimulant was coming into common use and was spreading throughout the city. This stimulant was clearly …
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Every time an American fills a prescription, a searchable electronic database record is made. This record is kept, like the paper records of a few decades ago, to allow for verification of medications dispensed in the U.S. But in the past, to access these records, enforcement agencies had to get a search warrant signed by a judge. This meant that the authorities had to have and show to the court …
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In a recently published study, it was found that a set of 4 genes (JUN, CEBPB, PRKCB, ENO2, or CEBPG) was shown to predict the diagnosis of heroin addiction with an accuracy rate of around 85 percent. This is an amazing development and could open the door to knowing who is at high risk of opiate addiction before the prescription is written. If similar markers can be found for …
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Have you ever wondered why some people always seem to be in pain? Or why someone can receive a prescription for a minor procedure and immediately feel drawn to drug use?
Scientists may have recently figured out one of the reasons for these behaviors, and they may start early in life. The developing neuron is remarkably similar to a tree. The branches are the dendrites that receive electrochemical signals from the …
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The practice of medicine has always been difficult. In the best of times, physicians must make fast decisions under very stressful conditions. Every time a doctor navigates a crisis, they reflect on what decisions they made and how they might improve. At least the good ones do. This soul-searching often involves discussions with colleagues and staff on the events and decisions made.
Mortality and morbidity discussions, M&M as we say, are …
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According to a report from the U.S. Department of Justice, 37 percent of the people in prison have a history of mental health problems. This was not always the case. The United States at one time had state mental health facilities, where those with mental illness could be treated. From 1870 to 1955, these numbers increased until it peaked at almost 600,000. This was 0.36 percent of the then population …
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We have a problem with current recommendations for depression treatment. Thirty-five percent of patients will not go into remission or get any relief at all from SSRIs and SNRIs. And even when it does work, it takes about six weeks to start having an effect.
The prevailing theory was that serotonin, abbreviated 5-HT, was the “satisfaction” neurotransmitter. Just as dopamine has been considered the pleasure neurotransmitter. Using selective serotonin reuptake inhibitors …
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What do you do if you get an administrative or court subpoena to produce “all” medical records on one or more patients? Are you sure that your electronic medical records can even create a true “legal” chart? With everything recorded chronologically? How would you know if something was left out?
And if you get an administrative or court subpoena for “all” medical records, what does that mean? What about access logs …
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In 1985, Mr. Charles McCrory was on trial. Charles had found his wife dead, and her family was convinced that he was responsible, despite the fact that Charles denied any involvement and just wanted to grieve in peace. There was no real evidence against him, but the state had an ace up its sleeve in the form of Dr. Richard Souviron.
Dr. Souviron was a forensic odontologist, which is a dentist …
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