Skip to content
  • About
  • Contact
  • Contribute
  • Book
  • Careers
  • Podcast
  • Recommended
  • Speaking
  • All
  • Physician
  • Practice
  • Policy
  • Finance
  • Conditions
  • .edu
  • Patient
  • Meds
  • Tech
  • Social
  • Video
    • All
    • Physician
    • Practice
    • Policy
    • Finance
    • Conditions
    • .edu
    • Patient
    • Meds
    • Tech
    • Social
    • Video
    • About
    • Contact
    • Contribute
    • Book
    • Careers
    • Podcast
    • Recommended
    • Speaking

Estrogen therapy and breast cancer: The pharmacist said no

Anne Katz, RN, PhD
Meds
September 28, 2014
Share
Tweet
Share

asco-logo

It’s not often that I find myself speechless. I have heard all sorts of stories in my office — as a sexuality counselor, I am often humbled by the trust that people place in me and how much they disclose about their private lives. But one conversation I had with a patient literally made my jaw drop.

The patient is a postmenopausal woman with stage III breast cancer. She had a mastectomy followed by radiation and chemotherapy and is now on an aromatase inhibitor. Like many women taking an aromatase inhibitor, she has significant vulvo-vaginal atrophy resulting in dyspareunia. Unlike other women with a similar history, she has not experienced a reactive loss of libido. She is very much in love with her partner — observing the two of them together in my office was joyful. They looked at each other often, finished each other’s sentences, and reminded me again how fortunate I am to do the work that I do.

I knew from the referral letter I had received from her oncologist that she had been prescribed local estradiol tablets at a low dose to treat the vulvo-vaginal atrophy. This in itself was unusual; most of the oncologists I have encountered do not prescribe local estrogen at all, and in fact, some warn me in their referral letters that I should under no circumstances even mention this treatment to the patient. But that’s a discussion for another day.

This woman had been using the tablets twice a week for about two months and told me that she thought that perhaps things were getting a little better. And that’s when she said that she had some difficulty getting the medication. I looked at her quizzically and motioned with my hand that she should continue.

“Well,” she said, “the pharmacist refused to fill the prescription.”

That’s when my jaw dropped and I lost all capacity for speech.

I know that pharmacists have refused to provide women with emergency contraception in some jurisdictions. I also know that some pharmacists refuse to dispense oral contraceptives to young women. This is allowed by law in some states, while in others it is permitted only if there is another pharmacy where the prescription can be filled. Some states allow the religious beliefs of the pharmacist to have an impact on their work. But why would a pharmacist refuse to fill a prescription written by an oncologist for a medication that has no religious connotations?

The provision of local estrogen to women with breast cancer is controversial. There are also geographic prescribing practices; I have spoken to physician groups across North America, and in some areas, prescribing local estradiol is an accepted practice, while in others, it is extremely rare. In a study of 285 gynecologists, 89% regarded the use of local estrogen therapy to be safe for women with breast cancer and would use it themselves if they had breast cancer.

But should a pharmacist not talk to the prescribing physician before taking a unilateral decision that prevented a patient from taking medication prescribed to improve her symptoms and quality of life? The patient told me that she contacted her oncologist and told her what had transpired at the pharmacy. It then took some time for the oncologist to speak to the pharmacist, and eventually her prescription was filled. However, this caused her a significant amount of distress and trust was lost; she initially lost trust in her oncologist after hearing the pharmacist’s refusal. After talking to her oncologist again, she no longer trusts the pharmacist.

There were other ways for the pharmacist to deal with this. He/she could have called the oncologist and asked for clarification in case the prescription was wrong. He/she could have explained to the patient (customer) that he/she had concerns and wanted to talk to the oncologist before filling the prescription. Or the pharmacist could have filled the prescription and trusted the oncologist. Or should the oncologist have included a note on the prescription that the prescriber and the patient were aware of the potential risks of the medication for this particular patient?

In the end, she used the medication and her sex life is improving. Her relationship with the pharmacist has not.

Anne Katz is a certified sexually counselor and a clinical nurse specialist at a large, regional cancer center in Canada who blogs at ASCO Connection, where this post originally appeared.  She can be reached on her self-titled site, Dr. Anne Katz.

Prev

Workplace wellness programs: Are they really failures?

September 27, 2014 Kevin 1
…
Next

Question why your relative needs to be at a rehab facility

September 28, 2014 Kevin 5
…

ADVERTISEMENT

Tagged as: Oncology/Hematology

Post navigation

< Previous Post
Workplace wellness programs: Are they really failures?
Next Post >
Question why your relative needs to be at a rehab facility

ADVERTISEMENT

More by Anne Katz, RN, PhD

  • Breast cancer’s silver lining

    Anne Katz, RN, PhD
  • Genital shrinkage is real. And so is the distress it causes.

    Anne Katz, RN, PhD
  • Do COVID restrictions in the office negatively affect patients?

    Anne Katz, RN, PhD

More in Meds

  • My persistent adverse reaction to an SSRI

    Scott McLean
  • Tofacitinib: a lesson in heart-immune health

    Larry Kaskel, MD
  • The case for regulating, not banning, kratom

    Heidi Sykora, DNP, RN
  • How India-Pakistan tensions could break America’s generic drug pipeline

    Adwait Chafale
  • The unfair war on buprenorphine

    Brian Lynch, MD
  • Drug giants face suit over hidden cancer risks

    Martha Rosenberg
  • Most Popular

  • Past Week

    • The dismantling of public health infrastructure

      Ronald L. Lindsay, MD | Physician
    • Rethinking cholesterol and atherosclerosis

      Larry Kaskel, MD | Conditions
    • The difference between a doctor and a physician

      Mick Connors, MD | Physician
    • How undermining physicians harms society

      Olumuyiwa Bamgbade, MD | Physician
    • Paraphimosis and diabetes: the hidden link

      Shirisha Kamidi, MD | Physician
    • What psychiatry can teach all doctors

      Farid Sabet-Sharghi, MD | Physician
  • Past 6 Months

    • The dangerous racial bias in dermatology AI

      Alex Siauw | Tech
    • When language barriers become a medical emergency

      Monzur Morshed, MD and Kaysan Morshed | Physician
    • The dismantling of public health infrastructure

      Ronald L. Lindsay, MD | Physician
    • Why doctors are losing the health care culture war

      Rusha Modi, MD, MPH | Policy
    • The hypocrisy of insurance referral mandates

      Ryan Nadelson, MD | Physician
    • A cancer doctor’s warning about the future of medicine

      Banu Symington, MD | Physician
  • Recent Posts

    • Paraphimosis and diabetes: the hidden link

      Shirisha Kamidi, MD | Physician
    • Silicon Valley’s primary care doctor shortage

      George F. Smith, MD | Physician
    • Why women in medicine need to lift each other up [PODCAST]

      The Podcast by KevinMD | Podcast
    • The problem with laboratory reference ranges

      Larry Kaskel, MD | Conditions
    • My persistent adverse reaction to an SSRI

      Scott McLean | Meds
    • Why carrier screening results are complex

      Oluyemisi Famuyiwa, MD | Conditions

Subscribe to KevinMD and never miss a story!

Get free updates delivered free to your inbox.


Find jobs at
Careers by KevinMD.com

Search thousands of physician, PA, NP, and CRNA jobs now.

Learn more

View 6 Comments >

Founded in 2004 by Kevin Pho, MD, KevinMD.com is the web’s leading platform where physicians, advanced practitioners, nurses, medical students, and patients share their insight and tell their stories.

Social

  • Like on Facebook
  • Follow on Twitter
  • Connect on Linkedin
  • Subscribe on Youtube
  • Instagram

ADVERTISEMENT

ADVERTISEMENT

  • Most Popular

  • Past Week

    • The dismantling of public health infrastructure

      Ronald L. Lindsay, MD | Physician
    • Rethinking cholesterol and atherosclerosis

      Larry Kaskel, MD | Conditions
    • The difference between a doctor and a physician

      Mick Connors, MD | Physician
    • How undermining physicians harms society

      Olumuyiwa Bamgbade, MD | Physician
    • Paraphimosis and diabetes: the hidden link

      Shirisha Kamidi, MD | Physician
    • What psychiatry can teach all doctors

      Farid Sabet-Sharghi, MD | Physician
  • Past 6 Months

    • The dangerous racial bias in dermatology AI

      Alex Siauw | Tech
    • When language barriers become a medical emergency

      Monzur Morshed, MD and Kaysan Morshed | Physician
    • The dismantling of public health infrastructure

      Ronald L. Lindsay, MD | Physician
    • Why doctors are losing the health care culture war

      Rusha Modi, MD, MPH | Policy
    • The hypocrisy of insurance referral mandates

      Ryan Nadelson, MD | Physician
    • A cancer doctor’s warning about the future of medicine

      Banu Symington, MD | Physician
  • Recent Posts

    • Paraphimosis and diabetes: the hidden link

      Shirisha Kamidi, MD | Physician
    • Silicon Valley’s primary care doctor shortage

      George F. Smith, MD | Physician
    • Why women in medicine need to lift each other up [PODCAST]

      The Podcast by KevinMD | Podcast
    • The problem with laboratory reference ranges

      Larry Kaskel, MD | Conditions
    • My persistent adverse reaction to an SSRI

      Scott McLean | Meds
    • Why carrier screening results are complex

      Oluyemisi Famuyiwa, MD | Conditions

MedPage Today Professional

An Everyday Health Property Medpage Today
  • Terms of Use | Disclaimer
  • Privacy Policy
  • DMCA Policy
All Content © KevinMD, LLC
Site by Outthink Group

Estrogen therapy and breast cancer: The pharmacist said no
6 comments

Comments are moderated before they are published. Please read the comment policy.

Loading Comments...