Have you heard the news?
“Flesh-eating ‘zombie’ drug ‘kills you from the inside out,'” headlines a CNN article.
“Tacoma market busted for selling ‘zombie’ drug,” barks out a Seattle-area news affiliate.
” Zombie drugs? Florida man stabs couple, eats dead man’s face in ‘random’ attack,” shouts a Syracuse news outlet.
Surely by now, you have heard chilling stories about …
As physicians, we are bound by four ethical principles. Beneficence (acting for the benefit of the patient), nonmaleficence (avoiding the harm of the patient), autonomy (respecting patients’ right to make their own decisions), and justice (fair and equitable treatment of patients). When people think of the ethical principles that guide physicians, “First, do no harm” comes to mind.
Unfortunately, our medical system in the United States is violating all four …
Fungi have a well-deserved surge in popularity. More mushroom varieties have found their way to grocery store shelves, shopping lists, and food blogs. Mushroom foraging is a trending activity as people endeavor to connect to nature. There is a growing market of mushroom coffee shops touting health-related boosts and “medicinal fungi” being sold as herbal teas and supplements. Innovative products have hit the market, from …
In November 2022, revisions to the United States Pharmacopeia’s (USP) General Chapter <797>, a standard for sterile pharmaceutical compounding – defined as the process of “combining, admixing, diluting, pooling, reconstituting, repackaging, or otherwise altering a drug product or bulk drug substance to create a sterile medication” – were published. USP <797> plays a major role in guiding …
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In this episode, we discuss personalized medicine with guest Ketan Desai, a physician-executive. We explore how Henry Ford’s mass production method influenced the pharmaceutical industry, and how personalized medicine presents new challenges. CAR T-cell therapy is an …
The timing of the United States Drug Enforcement Administration’s One Pill Can Kill campaign is crucial, considering the recent Carrollton teen tragedy in which Fentanyl-laced pills posing as oxycodone were distributed through a “juvenile dealer” to high school students who then sold the deadly drugs to high school and middle school students. Commenting on the dramatic increase in drugs laced with Fentanyl in North Texas, Nexus Recovery Center’s …
In March 2020, I was directing a federally qualified health center in rural New Mexico when the first flashover of COVID ripped through the state. In two days, the clinics transitioned from an entirely in-person model to a near-total remote model. The transformation was raw and unplanned, trialing mediocre communications platforms in real-time and stumbling through the vagaries of electronic prescribing. As we got our feet under us, unexpected upsides …
The United States and Canada started a movement that began as medical cannabis and quickly exploded into adult-use cannabis markets. However, the North American operators failed to properly regulate the processes from growing to manufacturing to compete in a global pharmaceutical-level market. Europe has taken the lead as the heavy-weight producer of truly medical-grade pharmaceutical cannabis flowers and products. Notably, many operators in the U.S. and Canada claim to produce …
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In this episode, we welcome Cindy Perlin, a licensed clinical social worker and chronic pain survivor, to discuss the ongoing issue of prescription painkiller abuse and the dangers of relying on medication to treat pain. Research shows …
Psychosis is a broad term that describes a change in the perception of reality. It can be caused by various conditions, including metabolic, psychiatric, neurologic, genetic, and other medical conditions, as well as licit and illicit substances, particularly cannabis. The Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) states that abnormalities define these disorders in one or more of the following five domains: delusions, hallucinations, disorganized thinking (speech), …
Driving around, searching for children’s Tylenol and a pharmacy that had the antibiotics my son needed, was not how I wanted to spend the holidays. I am not alone – shelves are bare, and antibiotics are in short supply as we head into the new year in the midst of a triple threat of COVID-19, flu, and RSV.
While this drug shortage is incredibly frustrating, at least there is …
An excerpt from Inside The Orphan Drug Revolution: The Promise of Patient-Centered Biotechnology.
Pre-revolutionary stirrings
Every revolution rises up against an order in need of reform. For the orphan drug revolution, that order was the pharmaceutical industry of the 1970s. Most pharma companies had been founded by entrepreneurial chemists or pharmacists decades …
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Less than a year ago, a position paper/meta-analysis was published whose authors concluded that the pain reliever acetaminophen, and products containing this compound, were contraindicated in pregnancy as they could result in premature or stillborn births or developmental defects. Earlier studies appeared more positive and resulted in recommendations for its use by professional and governmental organizations. The present authors acknowledged this disjunction and made both the routine recommendations for further …
Everyone knows the terrible toll the opioid epidemic takes on our society. It doesn’t matter where you live and how wealthy or educated you are, no one is immune. I watched as a colleague tried to help a child struggling with addiction, spending countless hours of worry and thousands of dollars, only to have the child succumb to an accidental opioid overdose. The emotional and financial cost on individuals and …
The American Cancer Society released its annual report on cancer statistics, showing that we have made clear and significant progress in treating numerous forms of cancer. The overall rate of death has declined steadily since 1991, translating to over 3 million lives saved.
Despite this progress, I still see room for improvement in a care model where patients too often slip through the cracks.
The National Cancer Institute identified that …
You’ve been swallowing things your entire life: breast milk (or formula), food––maybe a marble or small Lego. But did you know that swallowing pills is different?
Let’s start with how not to swallow a pill.
Sorry, but Bruce Willis in all five Die Hard movies is incorrect. You don’t just take a small handful of aspirin, toss them into your mouth, and jerk your head back while swallowing.
Not to mention, if you have …
I wondered whether to recommend Nuedexta for my elderly relative with worsening Alzheimer’s disease and daily spontaneous crying. Often she would deny feeling sad and couldn’t account for her sobbing. Avanir Pharmaceuticals released Nuedexta in 2010 to treat pseudobulbar affect: involuntary emotional outbursts due to certain neurologic conditions or brain injury. I wasn’t sure if these crying bouts qualified as pseudobulbar affect. But my biggest hesitation was the breathtaking …
“By God’s grace, Dr. Sal!”
“Yes, T.J.! What’s the good news?”
“Guess what Mr. Thompson’s potassium is now?”
“3.1 …”
“Wrong! 4.1!”
We high-fived each other immediately and breathed a huge sigh of relief. For six days straight, we’ve been giving Mr. T potassium through an IV and by mouth with little to no change in his potassium level.
He came to the hospital after being found passed out in his home. Very low initial blood …
Medical care in the United States is broken. The pandemic contributed, but we were well along this misdirected journey. There is a pathological push/pull between financial pressures applied by payors and health care systems to decrease costs, thereby generating profits versus the desire of providers to deliver outstanding care to patients. This is ingrained into our system as it is designed. The dynamic is further muddled by our unique medicolegal …
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