Skip to content
  • About
  • Contact
  • Contribute
  • Book
  • Careers
  • Podcast
  • Recommended
  • Speaking
  • All
  • Physician
  • Practice
  • Policy
  • Finance
  • Conditions
  • .edu
  • Patient
  • Meds
  • Tech
  • Social
  • Video
    • All
    • Physician
    • Practice
    • Policy
    • Finance
    • Conditions
    • .edu
    • Patient
    • Meds
    • Tech
    • Social
    • Video
    • About
    • Contact
    • Contribute
    • Book
    • Careers
    • Podcast
    • Recommended
    • Speaking

Treating hepatitis C with Sovaldi: Is it worth it?

Michael Kirsch, MD
Meds
October 22, 2014
Share
Tweet
Share

One catch phrase in health care reform is cost-effectiveness.  To paraphrase, this label means that a medical treatment is worth the price.  For example, influenza vaccine, or flu shot, is effective in reducing the risk of influenza infection.  If the price of each vaccine were $1,000, it would still be medically effective, but it would no longer be cost-effective considering that over 100 million Americans need the vaccine.

Society could not bear this cost as it would drain too many resources from other worthy health endeavors.  Economists argue as to which price point determines cost-effectiveness for specific medical treatments.  As you might expect, insurance companies and pharmaceutical companies might reach different conclusions when the each perform a cost-benefit analysis.

Remember, it’s not just cost we’re focusing on here, but also effectiveness.  If a medicine is dirt cheap, but it doesn’t work, it’s not cost-effective.  Get it?

Pharmaceutical companies who are launching extremely expensive medicines often boast about the medical benefits while they ignore the cost factor entirely.  We see this phenomenon regularly when the pharm reps come to our office or we are listening to a paid speaker.

Understandably, when expensive medical care is being paid for by a third party, patients and their families are not considering cost-effectiveness.  They are focused on their own health and welfare.  If the doctor advises that our mom needs chemo, we’re not wondering if the cost would be a fair allocation of societal resources.

A new hepatitis C (HCV) drug, Sovaldi, has recently been launched.  The 12-week course of treatment costs $84,000, or $1,000 a pill.  This bargain doesn’t include the costs of other drugs that are taken with Sovaldi as part of the treatment program.   The cost of curing HCV, a worthy objective, approaches $200,000 including the costs of medicines, physician services and laboratory and radiology testing.  Assuming that there are over 3 million Americans who are infected with HCV, the costs for curing them all approaches $300 billion.   That’s billion with a “B.”

Consider these facts before deciding if hepatitis C treatment is cost-effective:

  • Most patients with HCV feel well.
  • Most patients with HCV are not aware that they are infected.
  • The majority of patients with HCV will not develop cirrhosis or other serious complications of the disease.
  • Many HCV patients who are ‘cured’ of the virus would never have developed any health issues.  They were silently infected.

Here’s what’s needed:

  • Identifying HCV patients who are destined to develop severe complications.
  • Proof that treating these patients changes the course of their disease.
  • HCV treatment that is cost-effective.

TV or print ads about HCV treatment suggest that you “talk with your doctor to see if the drug is right for you.” When you do so, ask for the evidence that the treatment will allow you to live longer or live better.  Clearing your body of HCV sounds like a triumph and is marketed as such, but this might not change your life at all.

Information is power.  I wish there was some way this post could go viral.

Michael Kirsch is a gastroenterologist who blogs at MD Whistleblower. 

Prev

Nurses also have to confront to costs of care

October 22, 2014 Kevin 2
…
Next

Ebola and the tension between bureaucracy and medical judgment

October 22, 2014 Kevin 5
…

Tagged as: Gastroenterology, Medications

Post navigation

< Previous Post
Nurses also have to confront to costs of care
Next Post >
Ebola and the tension between bureaucracy and medical judgment

ADVERTISEMENT

More by Michael Kirsch, MD

  • Are Ozempic patients on a slow-moving runaway train?

    Michael Kirsch, MD
  • AI-driven diagnostics and beyond

    Michael Kirsch, MD
  • The surprising truth behind virtual visits

    Michael Kirsch, MD

More in Meds

  • Unregulated botanical products: the hidden risks of convenience store supplements

    Muhamad Aly Rifai, MD
  • “The meds made me do it”: Unpacking the Nick Reiner tragedy

    Arthur Lazarus, MD, MBA
  • The dangers of oral steroids for seasonal illness

    Megan Milne, PharmD
  • L-theanine for stress and cognition

    Kamren Hall
  • The AI innovation-access gap in medicine

    Tiffiny Black, DM, MPA, MBA
  • How deprescribing in psychiatry offers a path to safer care

    Muhamad Aly Rifai, MD
  • Most Popular

  • Past Week

    • The blind men and the elephant: a parable for modern pain management

      Richard A. Lawhern, PhD | Conditions
    • Is primary care becoming a triage station?

      J. Leonard Lichtenfeld, MD | Physician
    • The dangers of oral steroids for seasonal illness

      Megan Milne, PharmD | Meds
    • Catching type 1 diabetes before it becomes life-threatening [PODCAST]

      The Podcast by KevinMD | Podcast
    • A pediatrician’s reckoning with applied behavior analysis [PODCAST]

      The Podcast by KevinMD | Podcast
    • Understanding alternative drug funding programs

      Martha Rosenberg | Policy
  • Past 6 Months

    • The blind men and the elephant: a parable for modern pain management

      Richard A. Lawhern, PhD | Conditions
    • Is primary care becoming a triage station?

      J. Leonard Lichtenfeld, MD | Physician
    • Psychiatrists are physicians: a key distinction

      Farid Sabet-Sharghi, MD | Physician
    • Why feeling unlike yourself is a sign of physician emotional overload

      Stephanie Wellington, MD | Physician
    • The U.S. gastroenterologist shortage explained

      Brian Hudes, MD | Physician
    • Accountable care cooperatives: a community-owned health care fix

      David K. Cundiff, MD | Policy
  • Recent Posts

    • The quiet bravery of breast cancer screening

      Michele Luckenbaugh | Conditions
    • How automation threatens medical ethics principles

      Muhammad Mohsin Fareed, MD | Conditions
    • When to test for pediatric seasonal allergies

      Dr. Tanya Tandon | Conditions
    • A doctor’s humbling journey through prostate cancer recovery [PODCAST]

      The Podcast by KevinMD | Podcast
    • The loss of storytelling with ambient AI systems

      Alexandria Phan, MD | Tech
    • Sustainable health care innovation: Why pilot programs fail

      Gerald Kuo | Conditions

Subscribe to KevinMD and never miss a story!

Get free updates delivered free to your inbox.


Find jobs at
Careers by KevinMD.com

Search thousands of physician, PA, NP, and CRNA jobs now.

Learn more

View 11 Comments >

Founded in 2004 by Kevin Pho, MD, KevinMD.com is the web’s leading platform where physicians, advanced practitioners, nurses, medical students, and patients share their insight and tell their stories.

Social

  • Like on Facebook
  • Follow on Twitter
  • Connect on Linkedin
  • Subscribe on Youtube
  • Instagram

ADVERTISEMENT

ADVERTISEMENT

  • Most Popular

  • Past Week

    • The blind men and the elephant: a parable for modern pain management

      Richard A. Lawhern, PhD | Conditions
    • Is primary care becoming a triage station?

      J. Leonard Lichtenfeld, MD | Physician
    • The dangers of oral steroids for seasonal illness

      Megan Milne, PharmD | Meds
    • Catching type 1 diabetes before it becomes life-threatening [PODCAST]

      The Podcast by KevinMD | Podcast
    • A pediatrician’s reckoning with applied behavior analysis [PODCAST]

      The Podcast by KevinMD | Podcast
    • Understanding alternative drug funding programs

      Martha Rosenberg | Policy
  • Past 6 Months

    • The blind men and the elephant: a parable for modern pain management

      Richard A. Lawhern, PhD | Conditions
    • Is primary care becoming a triage station?

      J. Leonard Lichtenfeld, MD | Physician
    • Psychiatrists are physicians: a key distinction

      Farid Sabet-Sharghi, MD | Physician
    • Why feeling unlike yourself is a sign of physician emotional overload

      Stephanie Wellington, MD | Physician
    • The U.S. gastroenterologist shortage explained

      Brian Hudes, MD | Physician
    • Accountable care cooperatives: a community-owned health care fix

      David K. Cundiff, MD | Policy
  • Recent Posts

    • The quiet bravery of breast cancer screening

      Michele Luckenbaugh | Conditions
    • How automation threatens medical ethics principles

      Muhammad Mohsin Fareed, MD | Conditions
    • When to test for pediatric seasonal allergies

      Dr. Tanya Tandon | Conditions
    • A doctor’s humbling journey through prostate cancer recovery [PODCAST]

      The Podcast by KevinMD | Podcast
    • The loss of storytelling with ambient AI systems

      Alexandria Phan, MD | Tech
    • Sustainable health care innovation: Why pilot programs fail

      Gerald Kuo | Conditions

MedPage Today Professional

An Everyday Health Property Medpage Today
  • Terms of Use | Disclaimer
  • Privacy Policy
  • DMCA Policy
All Content © KevinMD, LLC
Site by Outthink Group

Treating hepatitis C with Sovaldi: Is it worth it?
11 comments

Comments are moderated before they are published. Please read the comment policy.

Loading Comments...