Skip to content
  • About
  • Contact
  • Contribute
  • Book
  • Careers
  • Podcast
  • Recommended
  • Speaking
KevinMD
  • All
  • Physician
  • Practice
  • Policy
  • Finance
  • Conditions
  • .edu
  • Patient
  • Meds
  • Tech
  • Social
  • Video
  • All
  • Physician
  • Practice
  • Policy
  • Finance
  • Conditions
  • .edu
  • Patient
  • Meds
  • Tech
  • Social
  • Video
    • All
    • Physician
    • Practice
    • Policy
    • Finance
    • Conditions
    • .edu
    • Patient
    • Meds
    • Tech
    • Social
    • Video
    • About
    • Contact
    • Contribute
    • Book
    • Careers
    • Podcast
    • Recommended
    • Speaking
KevinMD
  • All
  • Physician
  • Practice
  • Policy
  • Finance
  • Conditions
  • .edu
  • Patient
  • Meds
  • Tech
  • Social
  • Video
    • All
    • Physician
    • Practice
    • Policy
    • Finance
    • Conditions
    • .edu
    • Patient
    • Meds
    • Tech
    • Social
    • Video
    • About
    • Contact
    • Contribute
    • Book
    • Careers
    • Podcast
    • Recommended
    • Speaking
  • About KevinMD | Kevin Pho, MD
  • Be heard on social media’s leading physician voice
  • Contact Kevin
  • Discounted enhanced author page
  • DMCA Policy
  • Establishing, Managing, and Protecting Your Online Reputation: A Social Media Guide for Physicians and Medical Practices
  • Group vs. individual disability insurance for doctors: pros and cons
  • KevinMD influencer opportunities
  • Opinion and commentary by KevinMD
  • Physician burnout speakers to keynote your conference
  • Physician Coaching by KevinMD
  • Physician keynote speaker: Kevin Pho, MD
  • Physician Speaking by KevinMD: a boutique speakers bureau
  • Primary care physician in Nashua, NH | Kevin Pho, MD
  • Privacy Policy
  • Recommended services by KevinMD
  • Terms of Use Agreement
  • Thank you for subscribing to KevinMD
  • Thank you for upgrading to the KevinMD enhanced author page
  • The biggest mistake doctors make when purchasing disability insurance
  • The doctor’s guide to disability insurance: short-term vs. long-term
  • The KevinMD ToolKit
  • Upgrade to the KevinMD enhanced author page
  • Why own-occupation disability insurance is a must for doctors

The synergy in obesity and cancer

Zelda Okia, MD
Conditions
January 8, 2021
Share
Tweet
Share

Over two-thirds of adults in the United States are overweight or obese, and approximately 88 million American adults have pre-diabetes. More than 84 percent of those with pre-diabetes are not even aware that they have it.

Both obesity and type 2 diabetes are associated with an increased risk of cancer development. The risk of type 2 diabetes is related to elevated insulin levels and other growth factors. A recent article in the journal Cell sheds light on a link in obesity.

Researchers from the Harvard Medical School fed mice a high-fat diet in the study, and the mice gained weight. They then injected the mice with cancer cells that developed into tumors. They found that in the mice fed a high-fat diet, there was a decrease in the number and activity of (CD8+) T-lymphocytes that help fight cancer.

The researchers found that mice fed the high-fat diet, and gaining weight also increased fatty acid molecules in their blood. These free fatty acids were used by the cancer cells for fuel and allowed them to thrive.

The cancer cells appeared to gobble up these molecules, so they were not available for use by the CD8+ immune cells. These cells, starved of the fatty acid molecules, showed decreased numbers within the tumors and an associated decrease in their cancer-fighting activity.

Thus cancer cells are not only able to hijack much-needed resources within the body for their own growth and development but utilize these very resources to cripple the body’s defense mechanisms to fight against it.

It makes me think of a recent coaching session with a client who told me how he hated to exercise. I asked him to think of the cells in his body as employees in his company. On his website, he celebrates the high level of excellence he demands within his company, which is reflected in the type of employee he hires.

I said it is highly unlikely he would hire someone who was chronically over-tired, disheveled in appearance, starved of proper nutrition, and physically depleted. Why then would he create such an environment for his own cellular employees?

Instead of focusing so heavily on his dislike of exercise, I encouraged him that he could instead focus on becoming an accurate reflection of excellence within his own body that is portrayed by his company.

Consuming foods that support his body and keep his cells healthy, strong, and adequately fueled with nutrients and exercise allows him to maintain peak performance and adequately replenish his energy stores.

I think that we can all learn from this example. Healthy eating, exercise, and even positive thinking do not feel heavy, burdensome, or tedious. If you focus on preparing and maintaining your body for peak performance at work, home, and play, this may help overcome any feelings of resistance that may arise when feeling pressured to lose weight.

If we begin to think of the cells of our body as eager employees who want nothing more than to present us in the best light, then perhaps we will be inspired to work hard and keep them performing at peak levels.

Zelda Okia is a pathologist and weight loss coach.

Image credit: Shutterstock.com 

Prev

The ethics of rationing care during COVID

January 8, 2021 Kevin 2
…
Next

Medicine is failing rural Americans

January 8, 2021 Kevin 1
…

Tagged as: Obesity

< Previous Post
The ethics of rationing care during COVID
Next Post >
Medicine is failing rural Americans

ADVERTISEMENT

Related Posts

  • Hormone replacement therapy is still linked to cancer

    Martha Rosenberg
  • We have a shot at preventing cervical cancer

    Lisa N. Abaid, MD, MPH
  • Who’s really to blame for the obesity epidemic?

    Peter Ubel, MD
  • Obstruction of medical justice: How health care fails patients with cancer

    Miriam A. Knoll, MD
  • Despite progress in cancer care, cost and equity challenges still must be addressed

    David M. Aboulafia, MD
  • Using the Avengers to explain how cancer treatments work

    Jennifer Lycette, MD

More in Conditions

  • What to expect at your first gynecologic visit

    Callia Georgoulis
  • The quiet hospital financial crisis threatening health care

    Ganesh Asaithambi, MD, MBA
  • Closing the execution reliability gap in health care systems

    Katherine Owen, RN
  • How pain management solves a refractory headache

    Kayvan Haddadan, MD
  • The silent patient experience in the exam room

    Michele Luckenbaugh
  • A nurse’s final reflection on life, death, and regrets

    Debbie Moore-Black, RN
  • Most Popular

  • Past Week

    • Rethinking the role of family physicians vs. specialists

      Ronald L. Lindsay, MD | Physician
    • A humorous parody of medical specialties and the modern patient

      Sidney J. Winawer, MD | Physician
    • Administrative burden is driving severe physician burnout

      Kayvan Haddadan, MD | Physician
    • Pharmacy closures threaten our entire public health system

      Timothy Lesaca, MD | Physician
    • Clinicians are failing at value-based care because no one taught them the system [PODCAST]

      The Podcast by KevinMD | Podcast
    • How an international medical graduate fought workplace retaliation

      Daniela Rizzo, MD | Physician
  • Past 6 Months

    • The controversy over Maintenance of Certification for grandfathered physicians

      Bernard Leo Remakus, MD | Physician
    • Why clinicians fail at writing expert reports

      Tracy Liberatore, Esq, PA | Conditions
    • Rethinking the role of family physicians vs. specialists

      Ronald L. Lindsay, MD | Physician
    • How hindsight bias distorts clinical medicine

      Olumuyiwa Bamgbade, MD | Physician
    • The cost of time constraints in primary care: Why doctors feel rushed

      Ann Lebeck, MD | Physician
    • Health insurance incentives and alternatives to opioids for chronic pain

      Molly Candon, PhD and Daniel Clauw, MD | Conditions
  • Recent Posts

    • Clinicians are failing at value-based care because no one taught them the system [PODCAST]

      The Podcast by KevinMD | Podcast
    • Why listening is the core of patient-centered care

      Claudy Bonne Année, MD | Physician
    • What to expect at your first gynecologic visit

      Callia Georgoulis | Conditions
    • Why relationship-centered care matters in medicine

      John Wei, MD | Physician
    • The quiet hospital financial crisis threatening health care

      Ganesh Asaithambi, MD, MBA | Conditions
    • Why I would never compromise on withdrawing care until I saw it firsthand [PODCAST]

      The Podcast by KevinMD | Podcast

Subscribe to KevinMD and never miss a story!

Get free updates delivered free to your inbox.


Find jobs at
Careers by KevinMD.com

Search thousands of physician, PA, NP, and CRNA jobs now.

Learn more

Leave a Comment

Founded in 2004 by Kevin Pho, MD, KevinMD.com is the web’s leading platform where physicians, advanced practitioners, nurses, medical students, and patients share their insight and tell their stories.

Social

  • Like on Facebook
  • Follow on Twitter
  • Connect on Linkedin
  • Subscribe on Youtube
  • Instagram

ADVERTISEMENT

  • Most Popular

  • Past Week

    • Rethinking the role of family physicians vs. specialists

      Ronald L. Lindsay, MD | Physician
    • A humorous parody of medical specialties and the modern patient

      Sidney J. Winawer, MD | Physician
    • Administrative burden is driving severe physician burnout

      Kayvan Haddadan, MD | Physician
    • Pharmacy closures threaten our entire public health system

      Timothy Lesaca, MD | Physician
    • Clinicians are failing at value-based care because no one taught them the system [PODCAST]

      The Podcast by KevinMD | Podcast
    • How an international medical graduate fought workplace retaliation

      Daniela Rizzo, MD | Physician
  • Past 6 Months

    • The controversy over Maintenance of Certification for grandfathered physicians

      Bernard Leo Remakus, MD | Physician
    • Why clinicians fail at writing expert reports

      Tracy Liberatore, Esq, PA | Conditions
    • Rethinking the role of family physicians vs. specialists

      Ronald L. Lindsay, MD | Physician
    • How hindsight bias distorts clinical medicine

      Olumuyiwa Bamgbade, MD | Physician
    • The cost of time constraints in primary care: Why doctors feel rushed

      Ann Lebeck, MD | Physician
    • Health insurance incentives and alternatives to opioids for chronic pain

      Molly Candon, PhD and Daniel Clauw, MD | Conditions
  • Recent Posts

    • Clinicians are failing at value-based care because no one taught them the system [PODCAST]

      The Podcast by KevinMD | Podcast
    • Why listening is the core of patient-centered care

      Claudy Bonne Année, MD | Physician
    • What to expect at your first gynecologic visit

      Callia Georgoulis | Conditions
    • Why relationship-centered care matters in medicine

      John Wei, MD | Physician
    • The quiet hospital financial crisis threatening health care

      Ganesh Asaithambi, MD, MBA | Conditions
    • Why I would never compromise on withdrawing care until I saw it firsthand [PODCAST]

      The Podcast by KevinMD | Podcast

MedPage Today Professional

An Everyday Health Property Medpage Today

Copyright © 2026 KevinMD.com | Powered by Astra WordPress Theme

  • Terms of Use | Disclaimer
  • Privacy Policy
  • DMCA Policy
All Content © KevinMD, LLC
Site by Outthink Group

Leave a Comment

Comments are moderated before they are published. Please read the comment policy.

Loading Comments...