Skip to content
  • About
  • Contact
  • Contribute
  • Book
  • Careers
  • Podcast
  • Recommended
  • Speaking
KevinMD
  • All
  • Physician
  • Practice
  • Policy
  • Finance
  • Conditions
  • .edu
  • Patient
  • Meds
  • Tech
  • Social
  • Video
  • All
  • Physician
  • Practice
  • Policy
  • Finance
  • Conditions
  • .edu
  • Patient
  • Meds
  • Tech
  • Social
  • Video
    • All
    • Physician
    • Practice
    • Policy
    • Finance
    • Conditions
    • .edu
    • Patient
    • Meds
    • Tech
    • Social
    • Video
    • About
    • Contact
    • Contribute
    • Book
    • Careers
    • Podcast
    • Recommended
    • Speaking
KevinMD
  • All
  • Physician
  • Practice
  • Policy
  • Finance
  • Conditions
  • .edu
  • Patient
  • Meds
  • Tech
  • Social
  • Video
    • All
    • Physician
    • Practice
    • Policy
    • Finance
    • Conditions
    • .edu
    • Patient
    • Meds
    • Tech
    • Social
    • Video
    • About
    • Contact
    • Contribute
    • Book
    • Careers
    • Podcast
    • Recommended
    • Speaking
  • About KevinMD | Kevin Pho, MD
  • Be heard on social media’s leading physician voice
  • Contact Kevin
  • Discounted enhanced author page
  • DMCA Policy
  • Establishing, Managing, and Protecting Your Online Reputation: A Social Media Guide for Physicians and Medical Practices
  • Group vs. individual disability insurance for doctors: pros and cons
  • KevinMD influencer opportunities
  • Opinion and commentary by KevinMD
  • Physician burnout speakers to keynote your conference
  • Physician Coaching by KevinMD
  • Physician keynote speaker: Kevin Pho, MD
  • Physician Speaking by KevinMD: a boutique speakers bureau
  • Primary care physician in Nashua, NH | Doctor accepting new patients
  • Privacy Policy
  • Recommended services by KevinMD
  • Terms of Use Agreement
  • Thank you for subscribing to KevinMD
  • Thank you for upgrading to the KevinMD enhanced author page
  • The biggest mistake doctors make when purchasing disability insurance
  • The doctor’s guide to disability insurance: short-term vs. long-term
  • The KevinMD ToolKit
  • Upgrade to the KevinMD enhanced author page
  • Why own-occupation disability insurance is a must for doctors

Baby cured of HIV: What’s the real story?

Paul Sax, MD
Conditions
March 25, 2013
Share
Tweet
Share

As undoubtedly you’ve heard by now, there’s another person cured of HIV out there — this time, it’s a baby born to an HIV-infected mother.

Here’s the story: The mother didn’t know she was HIV positive until delivery, and the baby was found to be infected by both HIV DNA and RNA right at birth. The doctors started combination antiretroviral therapy approximately one day later, essentially as soon as the results came back. There was a good response to treatment, with declining HIV viral loads over the next few weeks that quickly became undetectable.

Successful treatment continued for 18 months, at which time mom and baby were lost to follow-up; the mom stopped the baby’s antiretrovirals. When the two returned to care 5 months later, the baby’s HIV RNA and antibody were both negative — much to the surprise of the doctors. Supplemental testing, using evaluations similar to those done on the Berlin patient, did not yield any evidence of replication-competent virus, and the baby remains off therapy today.

In short, baby cured of HIV.  Stop the presses! (Do they still say that?)  Front page story, New York Times. Look at this Google News Page. My colleagues and I are all getting e-mails from our friends/family/etc. asking about this “breakthrough.”

And we’re kind of baffled. Because this case will have about as much immediate impact on the HIV epidemic in the United States as the prior cure — that’s right, virtually none. Maybe it will have an impact globally, but that will be a major challenge.

Thinking about it more, however, I understand why this is such compelling news:

  • It’s a baby. The media love stories about HIV in babies. The whole “innocent victim” thing is hard to shake.
  • It’s a cure. Can’t miss that. And the press is probably hypersensitive about not missing out, since they initially whiffed on reporting the last HIV cure. It was first presented at CROI in 2008 and barely got a peep. Took a resuscitation of the story by the Wall Street Journal and, ultimately, publication in the New England Journal of Medicine for the case to receive major media attention. For the record, rumor has it that a certain highly prestigious medical journal (hint) also initially whiffed on it, rejecting the case report when it was first submitted.
  • The public probably doesn’t really understand that HIV in babies is all but 100% preventable. Not emphasized nearly enough in most of the media reports is that the mom didn’t know she was infected until delivery, so she missed out on the key intervention for preventing HIV transmission — treatment of the mom during pregnancy. And since treating pregnant women has long been standard-of-care, pediatric HIV in the United States is vanishing, a real triumph of prevention. Fewer than 200 cases/year in this country, and counting (down).

So what are the practical implications of this case?

First, in developing countries with high HIV prevalence, where perinatal transmission remains a problem, strategies to aggressively treat the newborns of untreated HIV-positive mothers should be implemented pronto. Second, the case will probably teach us a bit more about how we might someday actually cure more than just a single person here and there.

But for now, the headline to this USA Today piece — “Child’s HIV Cure Won’t Mean New Treatments Immediately” — is the understatement of the year.

Paul Sax is the Clinical Director of Infectious Diseases at Brigham and Women’s Hospital. His blog HIV and ID Observations, is part of Journal Watch, where he is Editor of Journal Watch AIDS Clinical Care.

Prev

Twitter makes me a better doctor: 4 reasons why I use Twitter

March 25, 2013 Kevin 6
…
Next

The resurrection of coenzyme Q10: It's all about the money

March 26, 2013 Kevin 5
…

Tagged as: Infectious Disease

< Previous Post
Twitter makes me a better doctor: 4 reasons why I use Twitter
Next Post >
The resurrection of coenzyme Q10: It's all about the money

ADVERTISEMENT

More by Paul Sax, MD

  • An infectious disease doctor answers your COVID-19 and coronavirus questions

    Paul Sax, MD
  • When should physicians read the House of God?

    Paul Sax, MD
  • Should we write that patients are “pleasant” in medical notes?

    Paul Sax, MD

More in Conditions

  • AI-assisted therapy: Why supervision makes the difference

    Farid Sabet-Sharghi, MD
  • When language becomes the barrier: IMGs and autism diagnoses

    Ronald L. Lindsay, MD
  • Charles Bonnet syndrome: Why the blind see hallucinations

    Ceres Alhelí Otero Peniche
  • Geriatric diabetes management: Why strict A1c targets can harm seniors

    George James
  • Why progression independent of relapse activity is the silent driver of disability in multiple sclerosis

    Andreas Muehler, MD, MBA
  • A physician’s quiet reflection on January 1, 2026

    Dr. Damane Zehra
  • Most Popular

  • Past Week

    • Health care as a human right vs. commodity: Resolving the paradox

      Timothy Lesaca, MD | Physician
    • Why voicemail in outpatient care is failing patients and staff

      Dan Ouellet | Tech
    • My wife’s story: How DEA and CDC guidelines destroyed our golden years

      Monty Goddard & Richard A. Lawhern, PhD | Conditions
    • Why medical school DEI mission statements matter for future physicians

      Aditi Mahajan, MEd, Laura Malmut, MD, MEd, Jared Stowers, MD, and Khaleel Atkinson | Education
    • Why dietary advice changes: It is not the food, it is the world

      Gerald Kuo | Conditions
    • Oral Wegovy: the miracle and the mess of the new GLP-1 pill

      Shiv K. Goel, MD | Meds
  • Past 6 Months

    • How environmental justice and health disparities connect to climate change

      Kaitlynn Esemaya, Alexis Thompson, Annique McLune, and Anamaria Ancheta | Policy
    • Will AI replace primary care physicians?

      P. Dileep Kumar, MD, MBA | Tech
    • A physician father on the Dobbs decision and reproductive rights

      Travis Walker, MD, MPH | Physician
    • What is the minority tax in medicine?

      Tharini Nagarkar and Maranda C. Ward, EdD, MPH | Education
    • Why the U.S. health care system is failing patients and physicians

      John C. Hagan III, MD | Policy
    • Alex Pretti: a physician’s open letter defending his legacy

      Mousson Berrouet, DO | Physician
  • Recent Posts

    • Beyond weight loss: the expanding benefits of GLP-1 receptor agonists

      Zehra Haider, MD | Meds
    • Medical misinformation: Navigating vaccine hesitancy with empathy

      Christine J. Ko, MD | Physician
    • AI-assisted therapy: Why supervision makes the difference

      Farid Sabet-Sharghi, MD | Conditions
    • When language becomes the barrier: IMGs and autism diagnoses

      Ronald L. Lindsay, MD | Conditions
    • Simple choices prevent chronic disease [PODCAST]

      The Podcast by KevinMD | Podcast
    • The American Board of Internal Medicine maintenance of certification lawsuit: What physicians need to know

      Brian Hudes, MD | Physician

Subscribe to KevinMD and never miss a story!

Get free updates delivered free to your inbox.


Find jobs at
Careers by KevinMD.com

Search thousands of physician, PA, NP, and CRNA jobs now.

Learn more

View 2 Comments >

Founded in 2004 by Kevin Pho, MD, KevinMD.com is the web’s leading platform where physicians, advanced practitioners, nurses, medical students, and patients share their insight and tell their stories.

Social

  • Like on Facebook
  • Follow on Twitter
  • Connect on Linkedin
  • Subscribe on Youtube
  • Instagram

ADVERTISEMENT

ADVERTISEMENT

  • Most Popular

  • Past Week

    • Health care as a human right vs. commodity: Resolving the paradox

      Timothy Lesaca, MD | Physician
    • Why voicemail in outpatient care is failing patients and staff

      Dan Ouellet | Tech
    • My wife’s story: How DEA and CDC guidelines destroyed our golden years

      Monty Goddard & Richard A. Lawhern, PhD | Conditions
    • Why medical school DEI mission statements matter for future physicians

      Aditi Mahajan, MEd, Laura Malmut, MD, MEd, Jared Stowers, MD, and Khaleel Atkinson | Education
    • Why dietary advice changes: It is not the food, it is the world

      Gerald Kuo | Conditions
    • Oral Wegovy: the miracle and the mess of the new GLP-1 pill

      Shiv K. Goel, MD | Meds
  • Past 6 Months

    • How environmental justice and health disparities connect to climate change

      Kaitlynn Esemaya, Alexis Thompson, Annique McLune, and Anamaria Ancheta | Policy
    • Will AI replace primary care physicians?

      P. Dileep Kumar, MD, MBA | Tech
    • A physician father on the Dobbs decision and reproductive rights

      Travis Walker, MD, MPH | Physician
    • What is the minority tax in medicine?

      Tharini Nagarkar and Maranda C. Ward, EdD, MPH | Education
    • Why the U.S. health care system is failing patients and physicians

      John C. Hagan III, MD | Policy
    • Alex Pretti: a physician’s open letter defending his legacy

      Mousson Berrouet, DO | Physician
  • Recent Posts

    • Beyond weight loss: the expanding benefits of GLP-1 receptor agonists

      Zehra Haider, MD | Meds
    • Medical misinformation: Navigating vaccine hesitancy with empathy

      Christine J. Ko, MD | Physician
    • AI-assisted therapy: Why supervision makes the difference

      Farid Sabet-Sharghi, MD | Conditions
    • When language becomes the barrier: IMGs and autism diagnoses

      Ronald L. Lindsay, MD | Conditions
    • Simple choices prevent chronic disease [PODCAST]

      The Podcast by KevinMD | Podcast
    • The American Board of Internal Medicine maintenance of certification lawsuit: What physicians need to know

      Brian Hudes, MD | Physician

MedPage Today Professional

An Everyday Health Property Medpage Today

Copyright © 2026 KevinMD.com | Powered by Astra WordPress Theme

  • Terms of Use | Disclaimer
  • Privacy Policy
  • DMCA Policy
All Content © KevinMD, LLC
Site by Outthink Group

Baby cured of HIV: What’s the real story?
2 comments

Comments are moderated before they are published. Please read the comment policy.

Loading Comments...