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A physician wades into the swamp of vaccine denial

Christopher Johnson, MD
Physician
June 9, 2017
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I occasionally dip my toe into the constant Internet flame wars over the generous term “vaccine skepticism,” and the less generous “vaccine denial.”

If you’re looking to see one of these quickly, Twitter always has some ongoing vaccine fireworks. The character limit of Twitter tends to compress the exchanges into hurled invectives, only occasionally punctuated by futile pleas for calm. Many quickly devolve into exchanges between posters of what they believe to be crushing evidence in the form of an image or two.

A huge variety of message boards and blog comment streams can be just as vitriolic, and the posters are not confined to 140 characters. It’s a swamp, but it can be a fascinating swamp. Of course, full disclosure requires I say I am a stout defender of vaccine efficacy and safety, which is not surprising since I am a pediatrician with subspecialty training in infectious diseases and critical care. One particular talisman vaccine skeptics (I’ll be kind here) obsess over is the package insert found in the vaccine boxes. I’m often challenged on Twitter with an image of one and told to “read the insert, stupid.”

Here’s a fairly benign example of what one sees:

That one’s just kind of ominous. There are plenty more that make it sound as if vaccines are highly dangerous — if you just read the insert. Here’s what can easily result:

Are you terrified yet? No? Well, if you’re not, perhaps it’s because you have a broader understanding of what drug package inserts are and how they got there. The inserts are produced by the manufacturer of the drug, and they have long been required by the FDA to include them. Every drug has them, and you can actually see a huge compendium of what’s in them by referring to a book that has been around for many decades: the Physicians Desk Reference, or PDR.

For many years every licensed physician received these huge tomes in the mail every year. Mine always went straight into the trash bin anyway. Why? Because the package insert isn’t really used by anyone in using any drug. We use published scientific data and expert opinion in deciding how and when to use a drug. The PDR site has a pretty interesting disclaimer in fine print at the bottom:

PDR.net is to be used only as a reference aid. It is not intended to be a substitute for the exercise of professional judgment. You should confirm the information on the PDR.net site through independent sources and seek other professional guidance in all treatment and diagnosis decisions.

The package inserts are, in my opinion, mostly designed as an attempt to protect the manufacturers from liability for untoward outcomes. They throw in absolutely everything that seems remotely possible or has been anecdotally reported. And you should know the reporting system is not filtered at all, merely compiled. I’ve seen lists of side effects that include opposite things: constipation or diarrhea, high blood pressure or low blood pressure, and quite a few others. Vaccine package inserts are no different in this respect from those for a host of other drugs.

Even the insert for normal saline, which is salt and water, sounds kind of scary. Saline is one of the cornerstone treatments we use in pediatric critical care, yet the insert warns: “Safety and effectiveness of Sodium Chloride Injection, USP 0.9% … in pediatric patients have not been established.” This is pure nonsense. We inject it as quickly as possible all the time for severe shock.

I’ll end with this useful image, since vaccine skeptics do love to pepper their posts with dramatic images:

Christopher Johnson is a pediatric intensive care physician and author of Keeping Your Kids Out of the Emergency Room: A Guide to Childhood Injuries and Illnesses, Your Critically Ill Child: Life and Death Choices Parents Must Face, How to Talk to Your Child’s Doctor: A Handbook for Parents, and How Your Child Heals: An Inside Look At Common Childhood Ailments. He blogs at his self-titled site, Christopher Johnson, MD.

Image credit: Shutterstock.com

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A physician wades into the swamp of vaccine denial
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