Jumping on the recent TikTok trend of medical professionals sharing the things they would never do given their knowledge and expertise, I am sharing the five things I would never do as a board-certified allergist-immunologist.

1. I would never rely on a Primatene mist inhaler to treat my asthma or breathing symptoms alone. Primatene mist is a controversial over-the-counter epinephrine inhaler that can be used for mild intermittent asthma. This inhaler was banned seven years ago due to its reliance on a propellant containing ozone-damaging ingredients.

It returned to the store shelves a couple of years ago with a safer propellant, but here is the deal: Epinephrine is not considered a safe medication for asthma treatment. Albuterol is a safer and more effective medication to relieve bronchospasm.

In fact, the National Asthma Education and Prevention Program guidelines recommend against using epinephrine. In large part, epinephrine can exacerbate heart symptoms that mimic breathing or asthma symptoms. Patients who are self-medicating then can delay much-needed emergency care.

Asthma is not a do-it-yourself disease; it is primarily a disease of inflammation that results in more twitchy or spastic airways. Patients commonly underestimate the severity of asthma. Any patient with ongoing symptoms requiring bronchodilators should be on anti-inflammatory medication to treat the underlying cause of asthma. Overuse of bronchodilators has been associated with worse outcomes and increased fatalities, with approximately 3,500 people dying from asthma each year.

2. I would never use food sensitivity tests or food allergy panels to screen for foods that I should not be eating. Food sensitivity tests purport to tell folks which foods contribute to bloating, gas, fatigue, and headaches by testing for immune system response to particular foods. The problem is that the immune system does not mediate these reactions. Instead, they result from the food we eat, how it is digested and then fermented by our gut microbiome.

These tests instead demonstrate the memory our immune system has made to particular foods it has been exposed to. The levels that are measured in many instances may actually demonstrate tolerance to a particular food.

Skip the $250 price tag and keep a journal of the foods you are eating and the symptoms you are having. If you have trouble discerning particular triggers, use that money saved to schedule a visit with a dietician to review your journals for possible triggers.

Food allergy panels or a pre-selected group of food-specific IgE tests are also not recommended, especially in the absence of significant symptoms. Individual food IgE tests are best used to confirm clinical suspicion of a true food allergy. True food allergy symptoms include near immediate development of vomiting, mouth itching, hives, wheezing, swelling, or passing out. Anaphylaxis.

Hidden food allergies are not a thing. Food allergies are dramatic, messy, and scary.

My other frustration with these tests is that they stoke food fear, anxiety, and higher grocery bills. I have also seen a lot of folks severely limiting their diets as a result. Not only is the constant state of fight or flight bad for our health, but a less diverse diet also doesn’t do a body good. The diversity of our diet is key in helping support good gut and immune system health. Additionally, we know that limiting exposure to foods, especially in childhood, can result in the loss of tolerance and the development of true food allergies.

3. I would never ignore recurrent infections, especially repeat sinus infections. Recurrent infections are a red flag for allergists-immunologists for many reasons. In particular, we know that increased use of antibiotics is not without risks, including the development of allergies, weight gain, and severe diarrheal infections, among others.

In some instances, the recurrent infections are not infections but instead allergies which are treated much differently. Other times, they signal an immune deficiency or structural issues in the sinuses.

If you go to the urgent care or minute clinic for sinus infections more than one to two times every few years, it would behoove you to get this checked out.

Another good reason to talk with your allergist? If you think you are allergic to penicillin or amoxicillin, there is a really good chance you aren’t any longer. An allergist can help you sort this out pretty easily too! Why is this important? Having penicillin or amoxicillin listed on your chart dramatically increases the cost of your care and the risk of developing certain types of infections.

4. I would never rely on Benadryl to treat my severe allergic reaction. Epinephrine is the first-line treatment for anaphylaxis. Benadryl is a band-aid and only treats the symptoms. Epinephrine is needed to stop the reaction where it started. Fatalities during anaphylactic reactions have been associated with a delay in administering epinephrine.

Also, on a side note, allergists as a whole don’t like Benadryl (diphenhydramine). It does not work any faster than second-generation antihistamines such as Zyrtec (cetirizine), and has significantly fewer side effects. Additionally, topical formulations, i.e., Benadryl cream, commonly cause allergic rashes.

5. I would never use personal products with fragrance as an ingredient. Our skin is our largest organ, and although it functions as a barrier, it absorbs much of what we put on it.

Fragrance is a catchall term used to describe a mix of proprietary ingredients. Unfortunately, a loophole in U.S. law doesn’t require companies to disclose what exactly is in this mix. We know that these substances are associated with numerous health problems, the least of which may be their propensity to cause allergic rashes.

Fragrance mix was named the Contact Allergen of the Year in 2007 and is the third most common allergen positive on patch testing. These are particularly problematic for anyone with a history of sensitive skin or other skin disorders such as eczema, rosacea, or hives.

More concerning, many of the chemicals found in fragrance are endocrine disruptors (EDCs). These chemicals mimic the hormones in our bodies. Even very small amounts of these EDCs can have big effects on how our body functions. EDCs have been associated with kidney, nervous and respiratory system problems. Additionally, they have been implicated in infertility, premature puberty, and birth defects.

Kara Wada is a quadruple board-certified pediatric and adult allergy and immunology, lifestyle, and functional medicine physician, a Sjögren’s disease specialist, and a Sjögren’s patient herself. She spent nine years on faculty at The Ohio State University Wexner Medical Center, where she served as associate program director of the allergy and immunology fellowship and led the Mast Cell Center of Excellence.

In 2025, she left academic medicine to build the kind of practice she could not find as a patient: the Immune Confident Institute, a national direct-care immunology practice licensed in 27 states. She treats the patients the health care system sends ping-ponging between specialists, people with complex, chronic, multisystem disease including mast cell activation syndrome (MCAS), dysautonomia, Sjögren’s disease, immune dysfunction, and the seronegative and “in-between” diagnoses that do not fit neatly into a single specialty.

Her premise is simple: These patients are not the problem. Fragmented care is. Medicine has become exceptionally good at looking through microscopes while losing sight of the telescope, the bigger picture of the person in front of us. Her work challenges a health care culture that demands compliance when it should assume competence, and aims to make strategic, compassionate immune-directed care the standard, and the exam room a place where patients are finally seen, heard, and believed.

Most of her reach is built outside the exam room. Her YouTube channel drew roughly two million views this past year, and more than 100,000 people follow her work across platforms, including a Sjögren’s community of about 6,600. She founded and hosts the Virtual Sjögren’s Summit, now in its sixth year and drawing some 4,300 registrants worldwide. She appears regularly on national television and in the health press, including Prevention, SELF, Good Housekeeping, WebMD, Medscape, and MedPage Today, and she writes for KevinMD on the diagnoses that live in the shadows and the medical gaslighting that surrounds them.

A TEDx speaker and sought-after keynote, Wada speaks to clinician and patient audiences about complex immune disease, the experience of being disbelieved, and what changes when the physician is also the patient. She is also an unlikely pageant titleholder, having served as Dr. Ohio America 2022 and Dr. Midwest America 2023, and has written about how pageantry sharpened skills medicine rewards but rarely teaches.

She earned her medical degree with honors from the University of Illinois College of Medicine at Peoria and completed internal medicine-pediatrics residency, allergy and immunology fellowship, and clinician educator fellowship at The Ohio State University and Nationwide Children’s Hospital. She lives in Columbus, Ohio, with her medical school sweetheart turned husband, Akira, and their three children.

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