I still recall the ICU physician holding my hand and preparing me for the possibility I might not survive the blood clots in my lungs, pulmonary embolism. It was eighteen years ago when out of the blue, I found myself unexpectedly holding the hand of that gentle, concerned doctor, whose name I do not even know. My son was three years old at the time, and all I could think …
Patients are captive pharmacy benefits manager consumers
Frustration.
If you’ve treated patients with PTSD, I’m guessing that both you and your patients have experienced frustration at numerous points along the treatment course. And it’s understandable – up until this point, the efficacy of PTSD treatments has been notoriously poor. The best options aimed to diminish the severity of symptoms with a combination of therapy and daily medications.
However, the …
What doctors need to know about psychedelic medicine
Despite health professionals’ efforts at conveying the effectiveness of immunization, many African Americans remain skeptical about the COVID-19 vaccine.
Getting to the root of this distrust is critical as the Delta and Omicron variants stoke up the number of positive COVID-19 cases across the United States. And the spread of the virus is not uniform. According to the National Vital Statistics System, Black Americans incur the highest COVID-19 …
COVID-19 and the Tuskegee syphilis study
With apologies to the late Yankees slugger Yogi Berra, for pandemic-weary Americans, it’s like “déjà vu all over again,” as new lockdowns and mandatory mask mandates are being imposed across the globe.
The latest threat, the Omicron COVID-19 variant, has been a major source of breakthrough infections, including among those who have been fully vaccinated and boosted, such as United States Senators Elizabeth Warren and Cory Booker.
Pfizer, Moderna, Johnson & Johnson, …
Covaxin: Doomed to the dugout or ready to join the field of vaccine options?
A recent headline in my neighborhood newspaper read, “A Dentist Became a Top Opioid Buyer in W. Va. Now a Drug Firm Faces Penalty for Ignoring Red Flags.” The drug firm sent 25,400 hydrocodone pills and 3,600 Xanax to one Huntington, WV area dentist. The DEA raided the dentist’s office and shut it down. The dentist admitted to ordering the pills for personal use.
This summer, also right …
How drug distributors contributed to the opioid crisis
Attention-grabbing headlines suggest that our crucial COVID-19 pandemic tools—monoclonal antibodies and vaccines—are incompatible. Beyond the controversy rests an evidence-based reality: monoclonal antibodies and vaccines are complementary aspects of patient care. Both are powerful interventions that can prevent hospitalizations and deaths from this virus. After weeks of declining cases and hospitalizations, the United States is experiencing another surge of new infections likely due to multiple factors, including relaxed mask use in …
COVID-19 monoclonal antibodies are a bridge to vaccination
When the FDA approved Gilead’s Truvada (emtricitabine/tenofovir disoproxil) for HIV PrEP in 2012, it was a revolutionary step forward. The drug was safe and up to 99 percent effective in preventing HIV infection in at-risk individuals.
Then in 2019, Gilead received FDA approval for a second drug for PrEP called Descovy (emtricitabine/tenofovir alafenamide), with equivalent efficacy to Truvada. Recent research has shown that by the end of 2020, …
Is Descovy really the better option?
How did we Americans allow health insurers to dictate how physicians practice good medicine? The hypocritic oath says, “Do no harm.” We should not allow insurance company profits to prevent proper care for patients.
Our insurer is now telling our young adult son, a Crohn’s patient (Crohn’s is not yet a curable disease), who has been in remission since he began taking Remicade over 11 years ago to switch to a …
How did we let insurers run health care?
On Monday, November 1, an Orange County California Superior Court Judge said, in a tentative decision, that the opioid pharmaceutical companies were not responsible for the opioid crisis.
This particular case, going by the name of “The People of the State of California v. Purdue Pharma,” started in 2014. The judge’s ruling noted that neither party requested a trial by jury. The trial took place before the judge between April 19, …
The people vs. opioid pharma: Pharma wins again
There is an urgent need for innovation in cancer treatments. Although we’ve seen significant progress in indications for drugs treating particular diseases, cancer research data shows that 10-year survival statistics for cancers such as esophageal and lung cancer, for instance, have shown only a 10 percent increase, while pancreatic cancer has shown no significant improvement since the 1970s. The implementation of targeted therapies in cancer treatment is an …
The rise of targeted therapies: the era of the patient-focused approach
Ivermectin is an over 30-year-old wonder drug that treats life- and sight-threatening parasitic infections. Its lasting influence on global health has been so profound that two of the key researchers in its discovery and development won the Nobel Prize in 2015.
I’ve been an infectious disease pharmacist for over 25 years. I’ve also managed patients who delayed proper treatment for their severe …
Ivermectin is a Nobel Prize-winning wonder drug
Creative photography
Year after year, new medications find their way into the market, adding to the abundant and colorful world of pharmaceuticals.
Medications play a dual role in our lives, as they represent wellness and illness concomitantly. I am primarily fascinated by the human love-hate relationship with medicine in the form of dependency and liberation, desire and distaste, and hope and despair. On one …
The abundant and colorful world of pharmaceuticals
Woodworking / Illustration
The problem with the act of taking medications is that it’s so mundane that we don’t see any problem with it.
This machine-cut, flat, unemotional, same-size-fits-all object that we defencelessly welcome in our very private body has a role. Medications occupy our existence by interlocking with our cells and taking control of our body, fighting, provoking, sedating, and changing the music …
The ritual of taking medications: the pill wheel
Pyrography
Medicine bottles are mundane objects tightly woven into our daily lives, with the promise of happier moods, better sleep, and lower blood pressure. Nevertheless, nothing on these objects correlates with hope, faith, or a feeling of healthiness. I aspire to affix a face on these bottles to create conversations among medication manufacturers, prescribers, and dispensers, allowing them to explore what really happens …
Colorful pills don’t paint my world
The Food and Drug Administration (FDA) negated the recommendation of its expert panel and approved Aduhelm to treat Alzheimer’s dementia (AD), contending that the possible benefit trumped the lack of evidence of efficacy. The FDA was inexcusably in error in making this decision. Aside from the likely lack of benefit, the use of this drug can result in many negative consequences that make its use ethically questionable.
The manufacturer submitted two …
The FDA was wrong about Aduhelm
Photography
A person’s lifetime medication consumption has a familiar and predictable pattern. The more a person ages, the greater their number of taken medication. However, the public behavior in initiating medication has been changed compared to thirty years ago.
Nowadays, parents demand to get their hands on OTC meds for their infants and toddlers.
In this piece, I am interested …
The life cycle of medication consumption
Many drug ads in the Journal of the American Medical Association (JAMA) during the 1950s, 1960s, and 1970s would offend today.
In an ad for Valium, we are told that the woman pictured (“Jan”) is “psychoneurotic” because she is unmarried at age 35. “You probably see many such Jans in your practice,” says the ad—“The unmarrieds with low self-esteem. Jan never found a man to measure up to her father.”
Valium was …
These journal ads could not run today
An installation to explore the impact of medications in daily life
Bob is a typical patient at the pharmacy with a chronic illness. Bob, along with 30 other random patients whom I followed in the year 2017, had been picked up to explore the number of medications they consumed in an average year. Bob took 4,280 prescription pills (no data on OTC consumption) …
4280: the number of pills Bob took last year
Ketamine (colloquially called “K,” “Special K,” or “Vitamin K”) is a potent, dissociative anesthetic. More specifically, it is a nonselective NMDA antagonist that initiates a wide array of physiological effects, already having ingratiated itself to a wider audience through its potential for abuse. Once used primarily in veterinary medicine, ketamine in recent years, however, has seen its medical applications extend beyond the realm of anesthesia, with clinical options now including …
Ketamine’s non-anesthetic powers: Please wait for the science
When the “opioid crisis” is mentioned, most people think of heroin, prescription pills like oxycodone, or — more recently — the powerful synthetic opioid fentanyl. Fewer people would think of novel opioids like tianeptine, although an increasing number of Americans have taken this substance in the form of over-the-counter supplements like ZaZaRed or Tianna – often without knowing that the substance has opioid properties that can cause dependence and overdose. …
The complications of drug regulation
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