A case where thrombolytics were successfully used in massive pulmonary embolus
From UptoDate: “Thrombolytic therapy clearly accelerates the lysis of acute emboli, but no clinical trial to date has been large enough to conclusively demonstrate an improvement in mortality . . . Most pulmonologists agree that thrombolytic therapy is appropriate when PE is accompanied by hypotension or extreme hypoxemia.”
Use of thrombolytics for PE is always a ballsy call. The most devastating complication, intracranial hemorrhage, occurs in 3 percent in those who receive it for PE.
