For the past century, physicians have practiced within the framework of materialism: the belief that everything real can be measured, and everything measurable is real. But that worldview has been quietly eroded by physics itself. In the double-slit experiment, particles behave as waves of probability until observed, at which point they collapse into definite form. Later variations (such as Wheeler’s delayed-choice experiments) demonstrated that observation seems to determine not only the state but even the history of a quantum event. In other words, mind and meaning appear to have agency, a participatory role in shaping reality.
If observation and intention help form the physical world, then the universe may be built not from inert matter but from living ideas, dynamic patterns of information imbued with directionality and purpose. These ideas, acting through consciousness, may underlie what spiritual traditions have long called God or Spirit: the intelligent order that gives coherence to all things.
Illness as misalignment with universal order
Every physician encounters suffering that defies simple biochemical explanation. Chronic pain, depression, addiction, and anxiety often persist despite technically correct treatment. Such conditions, I believe, may reflect not only physiologic imbalance but also spiritual misalignment, a discord between a person’s lived ideas and the universal principles that sustain life. If the universe itself is an expression of ordered meaning, then health represents resonance with that order. The Stoics described this as living according to nature. In Jewish and Christian thought, it is alignment with divine law. Across traditions, the language differs, but the message is the same: harmony with truth sustains vitality; dissonance breeds disease.
Modern research supports this link. A 2012 meta-analysis of over 3,000 studies found that religious or spiritual involvement correlates with better coping, lower rates of depression and substance abuse, and even lower mortality. Further studies note that patients who find meaning in illness experience less suffering, even in terminal disease, and spirituality has been described as an essential determinant of health, influencing both immune and cardiovascular regulation.
The role of the physician
Engaging spirituality in medicine does not mean preaching. It means listening for meaning. Physicians can integrate the spiritual dimension through simple, respectful inquiry.
- What gives your life meaning or purpose?
- When you suffer, where do you find strength?
- Do you feel aligned with your deeper beliefs?
These questions open the space for patients to articulate not only their symptoms but their stories. In doing so, the clinician participates in restoring coherence between body, mind, and idea, between the seen and the unseen.
A medicine of meaning
If ideas have agency, then every medical encounter is an act of co-creation. Diagnosis, empathy, even the physician’s intention may ripple outward in ways our current science only begins to describe. Healing becomes a process of re-alignment, of re-entering harmony with the universal intelligence that animates both matter and mind. The next transformation in medicine will not arise from new devices or data streams, but from the re-integration of meaning. Health is harmony between body and idea, between the finite and the infinite.
Neal Taub is a palliative care physician.





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