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Rebuilding patient trust when medical advice is resisted

Fabrizia Faustinella, MD, PhD
Physician
May 10, 2026
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I would like to share with readers a story about a clinical encounter that challenged my ability to build trust amid fear and misunderstanding. As a practicing physician and medical educator, I have long been drawn to the emotional and ethical dimensions of patient care. While the story itself is not unique, it captures a recurring tension in our work, the gap that can emerge between clinical expertise and patient belief, and the consequences when trust begins to fracture. I hope it resonates with fellow clinicians who have navigated similar moments of frustration, reflection, and renewed resolve.

The fragile bridge of trust: lessons from a patient’s journey

She entered our walk-in clinic with urgency in her step and fear etched into her face. A single mother of three, Isabela believed she had a urinary tract infection (UTI) and was adamant she needed antibiotics. Her voice trembled, not with anger, but with desperation. She had missed work, felt unwell, and was terrified something serious was brewing inside her. Her children, she said, were depending on her. She could not afford to be sick. I listened, examined her, and ordered a urine test in our clinic. It was negative. More importantly, her symptoms did not align with a UTI. Isabela, a restaurant worker, had been experiencing back pain, likely caused by lifting heavy cases in the kitchen and carrying large trays.

This was my first clinical encounter with Isabela. I tried to meet her fear with compassion and her urgency with clarity. Using a wall-mounted educational unit, which allows to select relevant topics and display images and videos, I explained to Isabela that her condition was due to muscle strain, the rationale for not prescribing antibiotics, and the potential risks associated with unnecessary treatment. Nevertheless, in an attempt to give her peace of mind, I ordered a urine culture and reassured her that I would follow up with her once the results became available. I offered Isabela prescriptions for anti-inflammatory and muscle relaxant medications, but she left upset and unconvinced, as the possibility of kidney disease and infection weighed heavily on her mind.

Later that day, Isabela went to the emergency department, leaving her children at home alone. There, too, she was told antibiotics were not needed. Two days later, she was seen in her primary care clinic. Despite two negative urine cultures, she was finally given the prescription she had been seeking all along. By then, she had missed three days of work, relied on friends to care for her children, and visited three health care facilities. The emotional, financial, and systemic cost was significant. In her follow-up evaluation, she wrote that the doctors who had denied her antibiotics did not care whether she lived or died.

This story has stayed with me, not because it was unusual, but because it was painfully familiar. As physicians, we are trained to diagnose, treat, and educate. But we are also called to navigate the fragile terrain of trust. In this case, I felt deeply frustrated because I knew in my heart that I had done everything I was supposed to do. I listened. I explained. I reassured. And yet, I failed to convince her she was safe without antibiotics.

The roots and ripple effects of mistrust

Isabela’s mistrust was not born out of malice, but of fear, misunderstanding, and a deeply personal conviction that she knew what was best for her body, a belief so strong it overrode multiple professional opinions and objective test results. It was not just a disagreement. It was a disconnect.

As a Hispanic woman, Isabela was acutely aware of the high prevalence of kidney disease in her community, a condition often associated with serious illness and dialysis, experiences many families witness firsthand. In addition, the widespread belief that antibiotics can cure almost anything likely reinforced her expectations. I understood her. The spectrum of kidney disease weighed heavily on her mind and reassurance without antibiotics felt insufficient. I saw her vulnerability. But I also saw the ripple effects of her mistrust: unnecessary suffering, misplaced anxiety, increased costs, and emotional strain.

This kind of mistrust is not rare. It often arises when patients are denied not what they need, but what they believe they need. Antibiotics are a common example. Despite education, many patients still equate antibiotics with healing. When we say no, it can feel like abandonment, even when our intention is protection. But mistrust does not only stem from misconceptions. It can be fueled by cultural differences, past negative experiences, systemic inequities, low health literacy, and disinformation. For many, the health care system feels like a maze, confusing, impersonal, and intimidating. In that context, self-diagnosis becomes empowerment; resistance to medical advice and expertise becomes self-defense. We must recognize that trust is not automatic. It must be earned, nurtured, and sometimes rebuilt. And we must accept that even our best efforts may not be enough. There are moments when empathy, expertise, and evidence still fall short. And in those moments, the limits of our reach are painfully clear.

The dangers of appeasement over trust

This story does not have a tidy resolution. Isabela got her antibiotics, but not because she needed them, because someone gave in and, for reasons that remain unclear to me, decided to prescribe antibiotics without evidence of infection. That may have brought her peace, but it reinforced a dangerous cycle: one where mistrust wins and medicine loses. Some colleagues speculated that the physician in the primary clinic prescribed antibiotics in an effort to preserve trust or avert conflict, especially in light of what had unfolded in the days before. Yet doing something wrong, even for a seemingly good purpose, does not make it right. When clinicians attempt to secure trust by conceding to inappropriate requests or by departing from evidence-based care, they risk undermining the very foundation they hope to protect. What is offered in those moments is not trust, but appeasement, and appeasement is fragile, conditional, and ultimately corrosive to the integrity of the clinical relationship. It is only when true trust exists that clinicians can practice medicine aligned with science and ethics and patients feel safe enough to accept care.

So what can we do? We can continue to listen and to educate. We can advocate for culturally sensitive care and better health literacy. We can reflect on our own biases and strive to meet patients where they are, but while physicians carry the responsibility of earning trust through competence, compassion, consistency, and communication, these efforts can be to no avail without a willing patient. Trust in medicine is often spoken of as something clinicians must earn, cultivate, and protect. Less often acknowledged is the equally essential role of the patient in accepting trust. Trust is not a unilateral gift bestowed by the clinician, nor is it an outcome that can be guaranteed by technical competence or good intentions alone. It is, at its core, a relational act, one that requires willingness on both sides.

Maybe, trust cannot be built in a single visit in a walk-in clinic, where encounters are brief and relationships provisional, but even more importantly trust cannot be imposed or coerced. For patients, accepting trust means allowing space for professional judgment that may conflict with personal beliefs or expectations. This is not easy, particularly in moments of fear, vulnerability, or prior disappointment with the health care system. Yet without that willingness, even the most careful listening, clear explanations, and compassionate presence may fail to bridge the divide. Trust cannot take root where it is resisted.

Fabrizia Faustinella is an internal medicine physician.

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