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A world without antidepressants: What could possibly go wrong?

Tomi Mitchell, MD
Meds
May 9, 2025
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Imagine waking up one morning to a bold headline screaming: “New Global Law: All Antidepressants Abolished!” Just like that, no more Prozac, no more Zoloft—no more of those little pills that have helped millions keep their balance while navigating life’s emotional tightrope. Pharmacy shelves are wiped clean overnight, and suddenly, one of the pillars of modern mental health care is gone.

Before you clutch your chest and start breathing into a paper bag, let’s go there for a moment—what would life look like without antidepressants?

Would society unravel into chaos, or would we be forced to finally dig into the deeper issues we’ve been patching over with prescriptions? If we’re honest, do we have the guts to face what’s hiding underneath?

Because let’s face it: Our world already feels like a pressure cooker on most days. Without antidepressants, the cracks in our mental health system—and our society—wouldn’t just show; they’d split wide open.

So, buckle up. Let’s stroll through this imaginary world—equal parts dark comedy, stark reality, and a lot of empathy.

The grocery store: Where madness meets Aisle 5

Picture yourself at the grocery store. You’re just trying to grab a few things and get out with your sanity intact. But today? Sanity is nowhere to be found.

In Aisle 5, a grown man cries into a box of cornflakes because his favorite brand is sold out. His SSRI used to keep that kind of emotional tidal wave at bay, but not today. Meanwhile, a woman meticulously arranges apples by color in the produce section. Her OCD is running the show now.

And the checkout line? Oh, it’s a full-blown meltdown. People who used to keep their panic attacks in check are hyperventilating. Stripped of their mood stabilizers, others are furiously tweeting the store for not moving fast enough.

It’s bananas. And we haven’t even left the grocery store.

Schools: An uncontained classroom circus

Now, imagine the schools. Teachers have swapped out their lesson plans for survival strategies.

The classroom vibe? Think *Lord of the Flies*—but add glitter, crayons, and a lot of yelling. Kids with ADHD are bouncing off the walls. The teacher’s voice is lost in a sea of impulsive blurts, and meltdowns are part of the daily schedule.

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The school counselor’s office? Slammed. Without meds to help manage anxiety or depression, students are overwhelmed by academic demands and social stressors.

And the bullies? They’re too emotionally fried to torment anyone—bittersweet if it wasn’t so heartbreaking.

Education? It’s no longer about learning. It’s emotional triage, every single day.

Hospitals: The new insane asylums

Hospitals have always been chaotic—but now? Total war zones. Without medications to manage mood swings or psychosis, emotional breakdowns are more intense and far more frequent.

Psychiatric units are maxed out. Staff are hanging on by a thread, drained from de-escalating situations that, with the proper medication, might’ve never gotten so severe.

Security teams are beefed up. Trust me, ER doctors are spending more time handling psychiatric holds than actual medical emergencies. It’s exhausting.

But here’s what keeps me awake: Desperate people always seek relief. And without antidepressants, many are turning to alcohol, drugs, and high-risk behavior to cope.

It’s not just a mental health crisis—it’s a public health disaster.

Society: A perfect storm of mental illness

Let’s be honest here. A world without antidepressants isn’t just a little inconvenient or messy. It’s a society tipping over the edge.

This isn’t just about personal traumas or failed relationships. This is about a world that’s built to break us.

A society set up to fail

Let’s call it like it is. We live in a world where:

  • Safety nets have vanished. Social services are gutted, community support systems are non-existent, and people are one paycheck away from disaster.
  • Economic inequality is at an all-time high. The gap between the haves and have-nots is widening, and the dream of upward mobility is a cruel joke.
  • The pace of change is relentless. Technology evolves faster than we can adapt, leaving people disconnected, disoriented, and disposable.
  • Social media breeds anxiety and insecurity. We constantly compare ourselves to curated highlight reels, leading to feelings of inadequacy and isolation.
  • Climate change and geopolitical crises are pushing people into existential dread, with no clear path forward.

In short, we are living in a society that is a perfect petri dish for mental illness. And without antidepressants to paper over the cracks, the full extent of our collective despair would be laid bare.

The biology of mental illness: Not so simple

Alright, time to put on the white coat for a second. As a physician, I can’t leave this part out. Mental illness isn’t just about emotions or having a “bad day.” It’s rooted in complex biology and tangled up with our environment.

Yes, we know neurotransmitters like serotonin and dopamine are involved in depression and anxiety. But it’s not as cut and dry as “low serotonin equals depression.” The science is evolving, and we’re learning that social, psychological, and environmental factors are enormous pieces of the puzzle.

Sure, genetics can play a role, but they don’t act alone. Environmental stressors, trauma, and societal pressure often flip the switch on those genetic tendencies. As we sometimes say, biology loads the gun, but society pulls the trigger.

Take away medication without changing the world around us? You’re not healing anything. You’re just throwing gasoline on the fire.

The hard truth: Antidepressants aren’t enough

Now, don’t get me wrong—I’m not saying antidepressants are a magic cure. They’re not. But for a lot of people, they’ve been life-saving.

Still, no pill can fix poverty, no prescription can erase loneliness, and no antidepressant can undo social injustice.

If we’re going to seriously talk about getting rid of antidepressants, we’d better be ready to face the brokenness of the world that created the need for them in the first place.

Final thoughts: Can we handle the truth?

A world without antidepressants? It’d be scary, heartbreaking, and frankly, a mess. But it would force us to finally stare down some truths we’ve dodged for too long.

Because we live in a system that sets people up to fail, and unless we take on the deeper issues—inequality, disconnection, lack of support—mental illness will keep growing, with or without the meds.

So maybe the real question isn’t, “What if we abolished antidepressants?” Perhaps it’s, “Why have we built a world where so many people need them just to survive?”

That’s the uncomfortable truth. And it’s time we did something about it.

Tomi Mitchell is a board-certified family physician and certified health and wellness coach with extensive experience in clinical practice and holistic well-being. She is also an acclaimed international keynote speaker and a passionate advocate for mental health and physician well-being. She leverages over a decade of private practice experience to drive meaningful change.

Dr. Mitchell is the founder of Holistic Wellness Strategies, where she empowers individuals through comprehensive, evidence-based approaches to well-being. Her career is dedicated to transforming lives by addressing personal challenges and enhancing relationships with practical, holistic strategies.

Connect with her on Facebook, Instagram, and LinkedIn, and book a discovery call to explore how she can support your wellness journey. For those interested in purchasing her book, please click here for the payment link. Check out her YouTube channel for more insights and valuable content on mental health and well-being.

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A world without antidepressants: What could possibly go wrong?
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