The pilgrimage of my dreams included a suitcase full of diapers, extra pants, and a quiet prayer for dignity. Italy has always been a dream destination for me. As a Catholic, I consider Rome the Holy City of my faith, and this year’s Jubilee motivated me to visit the four Holy Doors. I also love art and culture, and Italy is home to many historic sites and great works of …
Oncology has long been described as a discipline ruled by biology. Tumor pathways, mutational signatures, margins, and survival curves dominate how we measure, categorize, and predict outcomes. We are taught early in training that tumor biology is king, and much of our decision-making revolves around this truth. Yet, after years of practicing surgical oncology in India, I have learned that biology alone rarely determines the fate of my patients. Culture …
These days, getting spun out into a state of worry and panic is just a click away: Turn on any device for constant updates on the chaos around us.
Adding to this, on a personal level, the last six years have been the most difficult and transformative period of my life. I had never imagined that I would experience and recover from the darkness of depression and suicidality six years ago, …
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Pediatrician Kelly Curtin-Hallinan discusses her article “My improbable survival of stage 4 cancer.” Kelly shares her year-long journey of facing a dire diagnosis, enduring rounds of tests, managing the anxiety of waiting …
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Physician-scientist Diego R. Hijano discusses his article “How humor builds trust in pediatric oncology.” Diego shares how personal loss and his own cultural and linguistic experiences shaped his approach to care, teaching …
An excerpt from Scary Diagnosis: Navigating Fear, Finding Strength, and Securing the Health Care You Deserve.
Doctors are the centerpiece of the health care system. In large part, they have designed it, written its rules, lobbied the government to support it financially, and, through doctor-friendly regulation, they are its main financial beneficiaries. For most patients, their doctor is not just the centerpiece of a huge system; they represent the entire …
People living with inherited bleeding disorders (including those with mild and moderate hemophilia and females affected by hemophilia) face persistent unmet needs that are often overlooked in clinical research and treatment guidelines. About twenty percent of mild hemophilia cases experience serious bleeding episodes, challenging current assumptions of their benign course.
Unmet needs
Diagnosis and awareness: Patients with mild and moderate hemophilia often face a delayed or missed diagnosis, leading to unrecognized and …
I never expected that iron deficiency anemia would change the course of my life. I felt off. Tired in a way that sleep could not fix. Foggy, weak, emotionally distant. At first, I thought I was just worn down from work and the daily grind. I was not myself, physically, mentally, or emotionally.
Eventually, I was diagnosed with iron deficiency anemia, a condition many associate with mild fatigue or simply “not …
Cancer care has long been associated with physical, emotional, and psychological hardship. But for many patients, a quieter burden (the financial strain of treatment) shapes their experience in equally profound ways. Increasingly referred to as financial toxicity, this form of distress is emerging as a key determinant of cancer outcomes. Yet it remains under-recognized in day-to-day clinical care.
The high price of staying alive
Financial toxicity describes the economic hardship caused by …
American medical schools and universities once led the world in biomedical discovery, in large part due to federal funding. Public investment in science helped eradicate polio, unlock the human genome, and develop life-saving treatments for diseases once considered death sentences. But that era of reliable federal funding is ending under the current White House administration – and America’s research enterprise is at risk of going with it.
Over the past decade, …
I have always despised the trope of the patient who pulls through against all odds, despite all evidence to the contrary. Yes, diagnoses can shift and treatment plans evolve, but the ultimate trajectory rarely strays far from the original suspicion. Still, I understand why those stories resonate.
As a resident, I cared for a teen who got a night off from treatment to get married, and another who went to prom …
I like quails. They resemble sparrows but are slightly larger. Quails are relatively quiet and easy to keep since they cannot fly much, unlike sparrows. They have a good lifespan as well. Since childhood, I have raised many quails, and I currently have two that I bought in 2023.
The quails have aged significantly, and the male has plucked many feathers from the female’s body. As a result, there are bald …
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Renowned fertility specialist Oluyemisi (Yemi) Famuyiwa discusses her article, “When bleeding disorders meet IVF: Navigating von Willebrand disease in fertility treatment.” She explains that von Willebrand disease (VWD), the most common inherited …
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I first grasped the disconnect between health care professionals and the public while designing a brochure for a cornea donation campaign.
My original concept featured a young boy smiling, wearing an eye shield—an approachable image meant to encourage public participation. But the overseeing specialist rejected it. He insisted instead on a clinical close-up of a post-surgical eye, sutures and all. To him, it represented medical success. To potential donors, it was …
I remember a night during my first year of residency in oncology when I was on call. It was after midnight, and I was sitting at the ward counter.
I often struggle to sleep during night shifts, especially when I’m the only doctor on call. I prefer to stay at the counter because I dread the thought of some terrible thing happening and not being able to reach the ward in …
Clinical trials are the cornerstone of progress in cancer treatment. Yet, paradoxically, the very patients these trials are designed to help often face the greatest obstacles to participation. While the concept of “patient-centered” clinical trials has been around for years, more than 20 percent of U.S. clinical trials fail to accrue a sufficient number of participants, forcing them to fold.
Why aren’t patients enrolling in clinical trials?
While there have …
Take a moment—not just to see where you are, but to remember how far you’ve come.
Through obstacles that once felt impossible.
Through stress that nearly broke you.
Through moments when the weight of it all made you question everything.
But still—you kept going.
Because medicine isn’t just a job. It’s a calling.
And here, decisions aren’t just professional—they’re life and death.
You meet people at their most vulnerable, in their most intimate realities.
There’s no room for …
The FDA is failing rare disease patients. I’m one of them.
I’ve been on elamipretide for three years now. It is the only treatment that has made a meaningful difference in my life with primary mitochondrial myopathy—a degenerative genetic condition that impairs how my cells convert food and oxygen into energy. Mitochondria provide over 90 percent of the energy our bodies need; when they fail, the highest-demand tissues—like muscle, brain, and …
An excerpt from A Return to Healing.
Patients often ask me to do whatever tests are necessary to make sure they don’t have cancer or any other really bad diseases. It’s called screening: Look for diseases before patients exhibit symptoms, then fix the problems before they can rear their ugly head. Many of my patients believe that they have had their lives saved this way, always by a caring and …
I am trapped in a circadian rhythm that I cannot escape from. I think it started when I finished my residency. And to make matters worse, this week it felt like I was also trapped in the series Squid Game. I awake about an hour before first light (sometimes as early as 4:30 a.m.) and almost instantly fall asleep about an hour after dusk if I am laying down. No …
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