GSK is hoping OTC Xenical (Orlistat) will be a blockbuster. Don’t expect miracles however. From UptoDate, here is the results of a meta-analysis of the prescription version:
Almost two-thirds of the subjects completed the first year of treatment. Weight loss at one year varied from 5.5 to 6.6 percent of initial body weight in the placebo groups and 8.5 to 10.2 percent in the orlistat groups.
