Conditions

Are we scared of the wrong environmental toxins?

Conditions

November 1, 2025

Like you, I receive many emails concerning environmental toxins. Many of their claims are based on conjecture rather than scientific evidence and are delivered in a panicked manner, implying that you or a family member is doomed if you do not act quickly. It is especially annoying that they often target minor issues rather than major ones. For example, they have emphasized the danger of artificial sweeteners. However, if one …

A doctor’s fight to repair, not replace

Xiang Xie

Conditions

November 1, 2025

Author note: This piece is based on a series of conversations with Dr. Meng Xu, one of China’s leading cardiac surgeons. His voice, vision, and uncompromising devotion to valve repair inspired every word. Though he prefers to remain out of the byline, his story is the one being told.

It was 11:48 p.m. on August 14, 2021, China’s Qixi Festival, a day for lovers and a celebration …

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A doctor’s fight to repair, not replace

The case for therapeutic nicotine use

Larry Kaskel, MD

Conditions

October 31, 2025

When most people hear nicotine, they picture stained lungs, cigarette ads, or sweet-flavored vapes. But nicotine isn’t tar, benzene, or formaldehyde. It’s a potent nicotinic acetylcholine receptor agonist with real neurochemical effects, and in carefully selected patients, it can help. I’ve been using nicotine gum and lozenges for years in patients with fatigue, mild depression, and ADHD, not as a miracle cure but as a targeted cognitive and mood-enhancing tool. …

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The case for therapeutic nicotine use

A nurse’s view on the broken health care system

Amanda Dean, RN

Conditions

October 31, 2025

We ran as fast as we could. I glanced up occasionally at the nurse straddling my patient, her blonde waves obscuring her face as she furiously attempted to restart a non-beating heart. We pushed the hospital bed down hallways and around corners, narrowly missing people-filled stretchers lining the Emergency Department. I stood in the back while the experts took over. If she was ready to leave this world, I wanted …

Carrier screening counseling must evolve

Oluyemisi Famuyiwa, MD

Conditions

October 31, 2025

Carrier screening has outgrown the language we still use to explain it.

For years, clinicians told patients they were either “a carrier” or “not a carrier.” But as the science has evolved, this binary approach is not only outdated; it is increasingly misleading.

Genetic carrier screening has entered a new era, and our counseling must evolve alongside it.

For decades, carrier screening was offered selectively based on ethnicity. Ashkenazi Jewish individuals were screened …

Why plain language isn’t enough for patients

Hamid Moghimi, RPN

Conditions

October 30, 2025

In modern medicine, the use of plain language is a fundamental clinical skill. This is especially critical when health decisions can profoundly affect a patient’s life, impacting their financial stability, ability to work, personal independence, and mental well-being, as well as their capacity for managing daily care, recognizing warning signs, and adhering to treatment plans. Considering the patient as a partner in their care, an informed decision can only be …

Is infection the real cause of heart disease?

Larry Kaskel, MD

Conditions

October 29, 2025

I was trained to treat heart disease like a plumbing problem. Cholesterol clogs the pipes, statins clear them out. LDL goes down, we high-five each other. But what if we’ve been chasing the wrong culprit all along?

A recent Japanese study looked at 50 plaques removed during coronary atherectomy. Every single one of those plaques tested positive for Chlamydia pneumoniae by PCR or immunostaining. That’s not “some,” or “most.” That’s …

Physician suicide prevention: a call to action

Muhamad Aly Rifai, MD

Conditions

October 29, 2025

I wrote last year about physician suicide as a silent epidemic. The silence is not lifting. The losses are getting closer. The grief is heavier. We all feel it. This month, we lost Dr. Nolan R. Williams. He advanced care for severe, refractory depression and pushed neural stimulation science forward. Then he died by suicide. His death landed like a shock wave across medicine and beyond and the …

Who wants to live to be a hundred?

Althea Halchuck, EJD

Conditions

October 29, 2025

Extreme longevity

People claim they want to live to be 100, yet is that a good thing? How you get there may make all the difference. Here’s my take on Blue Zones and the prospect of living to 100. “Blue Zone” is a nonscientific term popularized twenty years ago by Dan Buettner, a National Geographic explorer who studied five geographic regions where many people live to be over ninety or 100. …

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Who wants to live to be a hundred?

Grief and leadership in health care

Dana Y. Lujan, MBA

Conditions

October 28, 2025

I didn’t understand why, especially since I had just spoken with him before his travels. The day my son’s father, Joseph, died, I was sitting in a nail salon. A friend from the military called, offering condolences. I didn’t understand why; until I checked social media and saw the news of an airplane crash. My heart knew before my mind could process it.

Six years later, same month, just five days …

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Grief and leadership in health care

CRISPR therapy offers hope for diabetes

Cliff Dominy, PhD

Conditions

October 28, 2025

In a major advance in medicine, a man with type 1 diabetes is making his own insulin again, this time using genetically engineered donor islet cells. Researchers provided the new cells with an invisibility cloak to allow them to escape immune detection. After three months of follow-up, his body had not only accepted the new tissue but was quietly producing insulin. This single-patient proof-of-concept study gives hope to the millions …

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CRISPR therapy offers hope for diabetes

Rethinking cholesterol and atherosclerosis

Larry Kaskel, MD

Conditions

October 27, 2025

A recent Washington Post article called for earlier detection of atherosclerosis and a shift from “ischemia-centric” thinking to an “atheroma-centric” model. That’s progress, but it’s still missing the most important piece: Plaque isn’t the root cause.

For 50 years, we’ve built a trillion-dollar cardiology machine around the cholesterol hypothesis. Statins, PCSK9 inhibitors, ezetimibe, inclisiran, Lp(a) drugs, all circling the same biochemical drain. LDL plays a role, yes. But LDL is …

Why doctors need emotional skills to survive

Robin Stern, PhD and Marc Brackett, PhD

Conditions

October 27, 2025

HBO’s The Pitt collected thirteen Primetime Emmy nominations this year, winning both Outstanding Drama Series and Outstanding Lead Actor in a Drama Series for Noah Wyle. But the recognition was not just for great television. The series struck a cultural nerve because it captured something raw and real: the emotional side of medicine. Viewers saw the chaos of an emergency room after a mass casualty event, the head physician …

The debate on English tests for immigrant nurses

Lynne Moronski, PhD, MPA, RN

Conditions

October 26, 2025

As a research scientist who is devoted to ensuring that immigrant nurses have successful U.S. careers, the issue of internationally educated nurses’ (IENs’) cross-culture language competence has recently been both a sensitive and front-and-center issue pervading my work. In my more than 30 years in the health care sphere, the topic is now reaching a fever-pitch as IENs increasingly enter the U.S. health care workforce and play a critical role …

The frustrating bureaucracy of getting a vaccine

Richard A. Lawhern, PhD

Conditions

October 26, 2025

At age 81, I speak and write voluminously as a health care educator specializing in public health policy and practice for the treatment of pain and addiction. My wife and I are also careful about getting our periodic vaccinations for flu and COVID-19. A few days ago we responded to an invitation from our pharmacy to drop in for our shots on a walk-in basis. The process turned out to …

Healing from the pandemic’s mental toll

Zamra Amjid, DHSc, MHA

Conditions

October 26, 2025

The pandemic changed us in ways that cannot be measured by infection rates alone. Beyond the physical toll, it left lasting scars on our mental health. Fear, uncertainty, and isolation became daily realities. As a health professional and researcher, I wanted to understand how people could begin to heal. During my doctoral work, I studied adults who engaged in different wellness practices after the pandemic. Some found relief in nature: …

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Healing from the pandemic’s mental toll

The infectious hypothesis of Alzheimer’s disease

Larry Kaskel, MD

Conditions

October 25, 2025

When I tell colleagues that I offer Valtrex (valacyclovir) and low-dose lithium orotate to patients worried about developing Alzheimer’s, the silence in the room thickens. Someone always asks, “Where’s the randomized controlled trial?” That’s exactly the problem. We keep waiting for perfect evidence while the disease eats away at people’s brains.

I’m an internist and lipidologist who’s spent years watching the medical establishment chase the wrong villains, like cholesterol, salt, …

The high cost of PCSK9 inhibitors like Repatha

Larry Kaskel, MD

Conditions

October 23, 2025

When the FOURIER trial was published in 2017, cardiologists and lipidologists everywhere hailed it as proof that lowering LDL with PCSK9 inhibitors “saves lives.” But when you actually read the data, not the press releases, it’s hard not to shake your head.

Over a median of 2.2 years, evolocumab (Repatha) reduced nonfatal heart attacks by about 0.9 percent and had no significant impact on death. The absolute risk reduction for all-cause …

Why non-work stress fuels burnout

Perrette St. Preux, RN, MScPH

Conditions

October 23, 2025

While work-related stress continues to be a major cause of burnout, new research shows that non-work stressors like caregiving demands, financial instability, and personal life conflicts also greatly increase the risk. Yet, the dominant narrative has not caught up, and many still believe burnout is only a workplace problem, overlooking the deeper, life-wide imbalance it often reflects.

Recently, I spoke to a nurse on sick leave for the third time …

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Why non-work stress fuels burnout

Why wellness programs fail health care

Jodie Green & Kim Downey, PT

Conditions

October 23, 2025

Jodie Green and I have been following each other on social media for a couple of years, and we finally had a conversation a few months ago. We discussed our appreciation for the work each of us is doing to support doctors and all other health care professionals, including my efforts and Jodie’s with her organization, the Clinician Burnout Foundation. We’re amplifying meaningful resources that are available for …

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Why wellness programs fail health care