Drugs and prescribing

1,242 articles · Since 2007

Articles, page 6

A cautionary tale about pramipexole

November 4, 2025Nov 4, 2025

I never thought I'd be the cautionary tale. For decades, I worked at a financial company. I'm a youth sports coach, a husband, and a father of two. I've spent decades coaching, mentoring players, and proudly producing high school sports…

I never thought I’d be the cautionary tale.

For decades, I worked at a financial company. I’m a youth sports coach, a husband, and a father of two. I’ve spent decades coaching, mentoring players, and proudly producing high school sports telecasts. I built a life around leadership, precision, and community.

But none of that prepared me for what happened when I was prescribed pramipexole (Mirapex) to treat Parkinson’s.

The warnings were there: compulsive …

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A cautionary tale about pramipexole

My persistent adverse reaction to an SSRI

Scott McLean

November 2, 2025Nov 2, 2025

Two years ago, I took a single 20 mg dose of escitalopram. Like millions of others, I was prescribed this antidepressant with the expectation that it would help, or at worst, have mild side effects that would pass. Instead, I experienced an immediate and severe adverse reaction. What I could not have imagined then was that the symptoms would not resolve; they have persisted and, over time, have only worsened.

Since …

Tofacitinib: a lesson in heart-immune health

Larry Kaskel, MD

October 6, 2025Oct 6, 2025

When the FDA put a black box warning on tofacitinib in 2021, the message was blunt: more heart attacks, more cancers, and more blood clots. The warning came from the ORAL Surveillance trial, which followed over 4,000 patients with rheumatoid…

Heart attacks and strokes: About one extra event for every 111 patients treated over four years.

…

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The case for regulating, not banning, kratom

Heidi Sykora, DNP

October 3, 2025Oct 3, 2025

Kratom (Mitragyna speciosa) has become a topic of significant debate among clinicians, policymakers, and the public due to differing views on its safety, pharmacology, and regulatory requirements. A recent article raises important concerns about kratom’s pharmacological actions, potential for addiction, psychiatric risks, and regulatory challenges. Although the goal of protecting public health is admirable, it is crucial that discussions around kratom are rooted in current scientific evidence and avoid …

How India-Pakistan tensions could break America’s generic drug pipeline

Adwait Chafale

September 25, 2025Sep 25, 2025

With over 270 active drug shortages and growing global instability, the United States must protect itself from a worsening crisis in cancer care. The fragile supply of generic chemotherapy drugs like cisplatin, which is important for treating bladder, lung, and testicular cancer, could collapse if geopolitical tensions between India and Pakistan escalate further. To preserve this diminishing supply, the U.S. must reduce its overreliance on Indian pharmaceutical manufacturing and …

The unfair war on buprenorphine

Brian Lynch, MD

September 23, 2025Sep 23, 2025

In my years as a physician on the front lines of addiction and pain medicine, I have never encountered a medication as transformative as buprenorphine (Suboxone). I have seen patients, broken by years of opioid addiction, have their lives change within an hour of their first dose, ready to reclaim a life they thought was lost. For these patients, buprenorphine is as essential as insulin is for a person with …

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The unfair war on buprenorphine

Drug giants face suit over hidden cancer risks

Martha Rosenberg

September 20, 2025Sep 20, 2025

Bridgett Brown, a resident of California, developed breast cancer from using brand-name and generic versions of the antipsychotics Risperdal (risperidone) and Zyprexa (olanzapine) says a new lawsuit from the Wisner Baum law firm. Neither Brown or her two prescribing physicians…

Neither Brown or her two prescribing physicians knew or “had reason to know” that the drugs could cause breast cancer since the drug manufacturers “obfuscated and disclaimed such risks while promoting these dangerous, expensive drugs over safer, …

The diseconomics of scale: How Indian pharma’s race to scale backfires on U.S. patients

Adwait Chafale

September 16, 2025Sep 16, 2025

Why Indian pharmaceutical companies run the risk of driving up U.S. consumer drug prices when scaling too quickly: the diseconomics of scale. Why the U.S. looks to India as a global supply chain hub for medications India's pharmaceutical industry saves…

Why Indian pharmaceutical companies run the risk of driving up U.S. consumer drug prices when scaling too quickly: the diseconomics of scale.

Why the U.S. looks to India as a global supply chain hub for medications

India’s pharmaceutical industry saves U.S. consumers billions, but scaling too fast is a mistake. Premature scaling through mergers and acquisitions (M&A) is not just unsustainable, it is reckless and a recipe for inefficiency, error, and rising …

A psychiatrist’s 20-year journey with ketamine

Muhamad Aly Rifai, MD

September 4, 2025Sep 4, 2025

The day I first watched ketamine lift a human being out of despair, I was standing in a quiet room at the National Institute of Mental Health. The fluorescent lights hummed, the monitor ticked, and a young adult who had been drowning for months came up for air. Hours, not weeks. That speed rewired me as much as it rewired their brain. In the early 2000s, most of us were …

How drug companies profit by inventing diseases

Martha Rosenberg

September 4, 2025Sep 4, 2025

Funding from direct-to-consumer (DTC) "ask your doctor" drug ads has captured news media outlets and all but blocked important health stories like these. Read on. 1. "Hormone replacement therapy" (HRT) is back. It is said that those who forget the…

Funding from direct-to-consumer (DTC) “ask your doctor” drug ads has captured news media outlets and all but blocked important health stories like these. Read on.

1. “Hormone replacement therapy” (HRT) is back.

It is said that those who forget the past are doomed to repeat it, and nowhere is this more evident than the re-marketing of HRT to menopausal women who do not remember the first debacle (which increased the risk …

Every medication error is a system failure, not a personal flaw

Muhammad Abdullah Khan

August 29, 2025Aug 29, 2025

Every 24 hours, at least one person dies from a preventable medication error. Every hour, countless others suffer complications that could have been avoided with better systems. Yet despite billions invested in health care technology and training, these numbers are…

Here’s the uncomfortable truth: We have been solving the wrong problem.

For decades, health care has treated medication errors like individual failures — a tired nurse, a distracted doctor, a …

Why kratom addiction is the next public health crisis

Muhamad Aly Rifai, MD

July 29, 2025Jul 29, 2025

In recent years, kratom, a botanical herb indigenous to Southeast Asia, has surged in popularity across the United States. Marketed aggressively online and sold openly in vape shops, convenience stores, and specialty herbal outlets, kratom is often portrayed as a…

In recent years, kratom, a botanical herb indigenous to Southeast Asia, has surged in popularity across the United States.

Marketed aggressively online and sold openly in vape shops, convenience stores, and specialty herbal outlets, kratom is often portrayed as a natural remedy, an herbal escape from chronic pain, anxiety, and opioid withdrawal. But beneath the alluring veneer of wellness and relief lies a dangerous, largely unregulated substance capable of causing severe …

FDA delays could end vital treatment for rare disease patients

GJ van Londen, MD

July 11, 2025Jul 11, 2025

The FDA is failing rare disease patients. I'm one of them. I've been on elamipretide for three years now. It is the only treatment that has made a meaningful difference in my life with primary mitochondrial myopathy—a degenerative genetic condition…

The FDA is failing rare disease patients. I’m one of them.

I’ve been on elamipretide for three years now. It is the only treatment that has made a meaningful difference in my life with primary mitochondrial myopathy—a degenerative genetic condition that impairs how my cells convert food and oxygen into energy. Mitochondria provide over 90 percent of the energy our bodies need; when they fail, the highest-demand tissues—like muscle, brain, and …

Pharmacists are key to expanding Medicaid access to digital therapeutics

Amanda Matter

July 11, 2025Jul 11, 2025

More than 78 million Americans rely on Medicaid or CHIP for their health care. Yet many still cannot access FDA-approved digital therapeutics because their state does not include them in covered benefits. Prescription digital therapeutics (PDTs) are software-based treatments authorized…

Prescription digital therapeutics (PDTs) are software-based treatments authorized by the FDA. They are delivered through smartphones or tablets and are used to manage conditions such as substance use disorder, ADHD, diabetes, and chronic insomnia. For people who face long …

How medicine repurposing enables value-based pain management and insomnia therapy

Olumuyiwa Bamgbade, MD

July 8, 2025Jul 8, 2025

In today's evolving health care environment, value-based care is reshaping the future of medicine. The push toward value-based care demands innovative, cost-effective, and patient-centered solutions. A promising yet underutilized strategy is medicine repurposing, the practice of using existing medicines for…

In today’s evolving health care environment, value-based care is reshaping the future of medicine. The push toward value-based care demands innovative, cost-effective, and patient-centered solutions. A promising yet underutilized strategy is medicine repurposing, the practice of using existing medicines for new therapeutic purposes. Drug repurposing provides a strategic pathway to improving health outcomes while minimizing costs. A compelling example of this approach is the use of clonidine, a long-established cardiovascular …

Forced voicemail and diagnosis codes are endangering patient access to medications

Arthur Lazarus, MD, MBA

July 8, 2025Jul 8, 202510

I won't be using CVS pharmacies anymore. Sure, I may still need to send prescriptions their way as a physician—but as a consumer, I'm done. Why? CVS has recently implemented a new phone system that forces callers to leave a…

I won’t be using CVS pharmacies anymore. Sure, I may still need to send prescriptions their way as a physician—but as a consumer, I’m done.

Why?

CVS has recently implemented a new phone system that forces callers to leave a voicemail instead of waiting on hold. The idea is to streamline operations, letting pharmacy staff return calls when they have time. It’s supposed to manage call volume, reduce wait times, and shield …

From stigma to science: Rethinking the U.S. drug scheduling system

Artin Asadipooya

July 3, 2025Jul 3, 2025

In 1971, President Nixon initiated a battle that would reshape the United States: The War on Drugs. As a key part of that campaign, he enacted the Controlled Substances Act (CSA), which authorized the Drug Enforcement Administration (DEA) to categorize modern-day controlled substances into 5 “schedules” based on their “medical use, potential for abuse, and safety or dependence liability.” They range from Schedule I, which are substances with …

How drugmakers manipulate your health from diagnosis to prescription

Martha Rosenberg

June 27, 2025Jun 27, 2025

It is said that 57 percent of U.S. doctors receive drugmaker/industry funding and 66 percent of U.S. adults are now on prescription drugs. Any correlation? Drug ads now cast such a wide "symptom net," comedian Chris Rock said he expected…

It is said that 57 percent of U.S. doctors receive drugmaker/industry funding and 66 percent of U.S. adults are now on prescription drugs. Any correlation?

Drug ads now cast such a wide “symptom net,” comedian Chris Rock said he expected to hear, “Do you fall asleep at night and wake up in the morning? You might be suffering from ….”

Here are six ways drugmakers hijack U.S. medicine

Diagnosing. Once upon a time …

The food-drug interaction risks your doctor may be missing

Frank Jumbe

June 24, 2025Jun 24, 2025

As a health care professional, I've often observed how one critical aspect of medication safety and efficacy gets overlooked: food-drug interactions. Every day, we prescribe and dispense powerful medications — but what patients eat alongside those medications can completely alter…

As a health care professional, I’ve often observed how one critical aspect of medication safety and efficacy gets overlooked: food-drug interactions.

Every day, we prescribe and dispense powerful medications — but what patients eat alongside those medications can completely alter their effects.

This isn’t just a pharmacy concern. It’s a multidisciplinary issue that deserves greater attention from physicians, pharmacists, and patient educators.

The physician’s role: Asking the right questions

We often do a solid …

Why retail pharmacies are the future of diverse clinical trials

Shelli Pavone

June 10, 2025Jun 10, 2025

The importance of diversity in clinical trials is well-documented, yet unfortunately the lack of diversity still occurs at an alarming rate. As a result, we continue to have less effective treatments, poorer health outcomes, one-size-fits-all medicine that falls short of…

The reason for lack of diversity in clinical trials is similarly known, with language barriers, limited access to health care facilities …

Drugs and prescribing

Articles, page 6

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