Is Alzheimer’s an infectious disease?

Conditions
October 12, 2025

For decades, neurology has told us that Alzheimer’s disease is caused by toxic proteins (amyloid plaques and tau tangles) that clog the brain. Pharmaceutical companies have poured billions into anti-amyloid drugs designed to wash them away. The results? Repeated failures, high-profile disappointments, and a handful of marginal approvals with no meaningful improvement in patients’ lives. Sound familiar? In cardiology, we’ve built an entire industry on lowering LDL cholesterol. Statins move …

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Life after GLP-1s: How to sustain weight loss

Conditions
October 12, 2025

It should come as no surprise that GLP-1 receptor agonists have revolutionized the management of obesity and metabolic syndrome. These drugs have shown extraordinary promise in regulating appetite, promoting weight loss, and improving blood sugar control. Nearly one in eight adults (twelve percent) have taken a GLP-1 agonist, and forty-three percent of adults diagnosed with diabetes have used these therapies, numbers likely to have increased further in the last year …

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Teaching medical students what it is really like to be a physician

Physician
October 12, 2025

Physician burnout and physician suicide continue to plague the medical profession. Everyone knows the tragic statistic: one U.S. physician commits suicide each day. While some statistics report a decrease in the problem over time, the accuracy of these reports is questionable. The reality is that it is far too common.

The term burnout, while a necessary label, implies that a single factor causes it. In reality, each burned-out physician is different. …

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A new framework for depression recovery

Conditions
October 12, 2025

What if recovery from depression was not only about reducing symptoms, but about rekindling a person’s inner spark?

During my years as a Navy nurse in mental health, I witnessed countless people navigating the heavy fog of depression. Many were offered medication, therapy, or structured activity schedules. These approaches saved lives and improved outcomes. Yet sometimes, despite best efforts, patients still felt like they were going through the motions, managing symptoms …

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Why doctors are losing the health care culture war

Policy
October 12, 2025

The interview ends. The line goes dead. A senior CDC official has resigned, not because the science changed, but because the room did. Within forty-eight hours, CDC Director Monarez is fired by tweet, three senior leaders walk out, and a deputy from HHS (Jim O’Neill, a Silicon Valley investor turned political enforcer) is slotted in as acting CDC chief.

The headlines say turmoil. That is the polite word for capture.

Meanwhile, the …

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Innovations and barriers in colorectal cancer screening strategies [PODCAST]

Podcast
October 11, 2025
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Nurse practitioner Elisabeth Evans discusses her article “The critical role of nurse practitioners in colorectal cancer screening.” Elisabeth shares why colorectal cancer is the second-deadliest cancer in the U.S. yet remains under-screened, …

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Global surgery needs advocates, not just evidence

Education
October 11, 2025

In the world of global surgery, progress is a word we love to repeat. Since 2015, we have celebrated the drafting of National Surgical, Obstetric, and Anaesthesia Plans (NSOAPs), applauded World Health Assembly resolutions, and cited countless academic papers. But walk into a district hospital in a low- or middle-income country, and the patient waiting for a life-saving operation will not feel that progress. For them, the promises of global …

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The hypocrisy of insurance referral mandates

Physician
October 11, 2025

Every week, I see patients not because they need to, but because their insurance company says they must. A patient came in recently for one reason only: Her insurer required a referral before she could see a specialist. She didn’t want to. I didn’t need her to. But we both had no choice. After a 20-minute visit neither of us needed, I did what the insurer required: document, click, submit. …

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The timeless art of diagnostic reasoning

Physician
October 11, 2025

The patient was in her forties. She experienced chest pain, but it did not appear to be “classic.” Her ECG was normal. Her labs did not raise alarms. The team leaned toward anxiety. Hours later, she went into cardiac arrest from a heart attack. That silence after the code still stays with me. We anchored on the first test. We closed the case too early. We stopped listening to her …

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Why health self-advocacy is an essential life skill

Conditions
October 11, 2025

Money management and career planning are considered life skills (but the skill that shapes health self-advocacy) deserves the same status. Without it, care suffers. My family member was recovering from surgery, facing medication safety concerns, severe anxiety, and the need for constant care. At the same time, I was managing my own records and preventive health. Like so many women, I had become the family’s chief health executive, carrying responsibilities …

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How functional medicine helps where conventional care falls short [PODCAST]

Podcast
October 10, 2025
YouTube video

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Internal medicine physician Sally Daganzo discusses her article “How functional medicine fills the gaps left by conventional care.” Sally explains how a systems-based, evidence-informed approach can uncover root causes of complex conditions …

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What MS can teach cardiologists about disease

Physician
October 10, 2025

At the recent ECTRIMS Congress in Barcelona, researchers presented data that should make every specialist pause. In a claims analysis of nearly 70,000 patients with multiple sclerosis (MS), 98 percent of infections were first detected not in neurology clinics, but in primary care and other non-neurology practices. Even “serious” infections requiring hospitalization were almost entirely picked up elsewhere. The message was clear: Specialists, by design, often miss the forest for …

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What an active shooter taught me about being a doctor

Physician
October 10, 2025

“Do you know what it feels like, to know you could die at any moment?” His words linger in the air, heavy, long after the threat of violence has passed, long after our team has calmed him with words and soft gestures. It is not the first time a patient’s family member has swung at me, nor will it be the last. But it is the first time with a …

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Physician leadership in moments of crisis

Physician
October 10, 2025

There’s a common belief that leadership requires a title after your name, an office on the top floor, and people looking to you for direction. But in medicine, leadership happens at every level.

Take me, for example. I’m an attending physician, whose role on the team is as a hospitalist. In the hierarchy of medicine, it’s easy to dismiss this role as “just a physician.”

Yet there’s nothing “just” about it when …

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A pilgrimage to Italy with prostate cancer

Physician
October 10, 2025

The pilgrimage of my dreams included a suitcase full of diapers, extra pants, and a quiet prayer for dignity. Italy has always been a dream destination for me. As a Catholic, I consider Rome the Holy City of my faith, and this year’s Jubilee motivated me to visit the four Holy Doors. I also love art and culture, and Italy is home to many historic sites and great works of …

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Are doctors’ emotions fueling the opioid crisis?

Conditions
October 10, 2025

It should be obvious by now, but somehow it is not: Physicians are not immune to the same emotions that govern human behavior everywhere else. We like to imagine that our white coats and years of training somehow grant us a protective immunity to fear, to shame, to the raw surge of emotion that can stop us in our tracks. The truth is, physicians and other medical professionals are just …

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A medical student’s journey to Tanzania

Education
October 10, 2025

If you have grown up under the realities of western medicine, you likely have general grievances about the financial cost of care, the inconvenience of scheduling and attending appointments, and the long wait times at the emergency room or to see a specialist. As a medical student and an occasional patient, the majority of my experiences have been in this philosophy of health care where everyone is entitled to quality …

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How therapy helps uncover hidden patterns that shape our lives [PODCAST]

Podcast
October 9, 2025
YouTube video

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Anesthesiologist and clinical mental health counselor Maire Daugharty discusses her article “How therapy helps uncover hidden patterns.” Maire explains how psychotherapy leverages the brain’s pattern-seeking nature to reveal implicit beliefs formed in …

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Focal therapy for prostate cancer: a new option

Conditions
October 9, 2025

Prostate cancer treatment is evolving, and focal therapy is gaining relevance as part of that change.

For decades, patients and their physicians have had limited options: whole-gland treatments like radical prostatectomy or radiation, or active surveillance. But what about the men who fall somewhere in between? What about those who need more than monitoring, yet want to avoid the significant side effects associated with whole-gland therapy?

That is where focal therapy enters …

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The power of ordinary joy for physician well-being

Physician
October 9, 2025

I just spent a weekend doing absolutely nothing. Well, nothing memorable, anyway. The week before, I’d been on home call during an Epic upgrade. If you’ve lived through one of these updates, you know the chaos. In addition to the usual phone calls about echo results, arranging studies, and communicating with referring physicians, I was getting a constant stream of secure chat notifications updating me on the system’s progress. These …

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