GLP-1 agonists and weight loss: Treating the disease, not the number
Modern medicine loves numbers. LDL. A1c. BMI. Tumor diameter. Pounds lost. They are easy to measure, easy to track, and easy to celebrate. But none of them are the disease itself.
As GLP-1 prescribing accelerates and insurers increasingly define success by weight reduction, we are repeating a familiar mistake: Elevating a surrogate marker to the status of a biological endpoint.
BMI was never designed to diagnose disease in individuals. Adolphe Quetelet created …
GLP-1 agonists and weight loss: Treating the disease, not the number
