Is Lp(a) testing the new messiah?

Conditions
November 6, 2025

I just read yet another article praising the new messiah of cardiology (Lipoprotein(a)) and urging every physician in America to start testing for it. The tone was familiar: solemn, scientific, and a little evangelical.

The message? “Measure Lp(a) once in every patient.”

The subtext? “Because we finally found the missing piece.”

If this feels like déjà vu, that’s because it is. We’ve been here before: first with total cholesterol, then LDL, then HDL …

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Is Lp(a) testing the new messiah?

Is it time for the VA to embrace virtual care?

Tech
November 6, 2025

Is it time for the Department of Veterans Affairs (VA) to fully embrace virtual care?

The VA has long been one of America’s great health care innovators. From pioneering electronic health records to building one of the first truly integrated care systems, the VA has often been decades ahead of the private sector.

But today, the system is straining. Nearly 94 percent of VA facilities face physician shortages, and 79 …

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Is it time for the VA to embrace virtual care?

Pharmacy benefit manager reform vs. direct drug plans

Meds
November 6, 2025

Much has been made of the move by President Donald Trump and the pharmaceutical industry to offer direct-purchase drug programs at heavily discounted rates. Following the announcement of these new programs and TrumpRx, we’ve heard news and opinion pieces from every major outlet, but missing in the conversation is one of the most important voices: the patient. Key questions remained unanswered:

“What does this mean for my care?”

“Does this work with …

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Pharmacy benefit manager reform vs. direct drug plans

The psychological trauma of polarization

Physician
November 6, 2025

The human psyche is built for connection. Our evolutionary history, our families, and our communities shape us to seek cooperation, mutual respect, and shared purpose. We are, by design, social beings whose sense of safety depends on trust and belonging.

When that natural orientation toward unity is fractured; when instead we encounter hostility, harsh language, or dehumanization, it cuts against the grain of who we are. What might once have been …

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The psychological trauma of polarization

Quality metrics in medicine vs. patient trust

Physician
November 6, 2025

The woman sits across from me, hands folded around a list of her medications.

We review the cholesterol guidelines. I explain the evidence. She listens carefully, then says, almost apologetically, “Doctor, I know what the data says. I just don’t want to take another pill.”

There is no anger in her voice, only fatigue, the quiet exhaustion of someone who has lived long enough to know her own limits.

I pause, because this …

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Quality metrics in medicine vs. patient trust

Understanding post-vaccination syndrome in real-world medicine [PODCAST]

Podcast
November 5, 2025
YouTube video

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Internal medicine physician Harry Oken discusses his article “mRNA post vaccination syndrome: Is it real?” In this episode, Harry explores the science, uncertainty, and human stories surrounding post-vaccination syndrome (PVS) linked to …

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Understanding post-vaccination syndrome in real-world medicine [PODCAST]

Why DPC market-model fit matters most

Physician
November 5, 2025

In my previous article, I examined why direct primary care (DPC) practices fail, focusing on financial modeling, compliance risks, and the gap between what’s legal and what’s sustainable. But there’s a more fundamental issue that precedes all of those concerns: market-model fit.

The direct primary care community loves to debate panel size, membership pricing, and model purity. We dissect what went wrong when practices fail. We blame insufficient commitment, poor …

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Why DPC market-model fit matters most

The quiet will of a healer

Physician
November 5, 2025

As physicians, we are trained to balance truth with compassion, and science with empathy. It’s a delicate balance and an uncertain path. Medicine requires both strength and vulnerability because navigating this balance can leave ambiguity as to whether the healer’s words heal as much as intended. These moments also reveal the tension between knowledge, ethics, and emotion, a struggle between the imperative to speak to fact and the human need …

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The quiet will of a healer

Clear communication is kind patient care

Physician
November 5, 2025

I walked into the exam room to meet with a woman recently diagnosed with breast cancer. She had undergone a PET CT scan to evaluate for the extent of her disease. She sat on the exam table, clearly very anxious and upset. She told me that she had been up most of the night with her PET scan report, Googling about different organs and language that she did not understand. …

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Clear communication is kind patient care

Helping children overcome anxiety [PODCAST]

Podcast
November 4, 2025
YouTube video

Subscribe to The Podcast by KevinMD. Watch on YouTube. Catch up on old episodes!

Physician executive Mona Potter discusses her article “When anxiety runs the show: How medication can help kids thrive.” In this episode, Mona explores how clinical anxiety differs from everyday worry, why it …

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Helping children overcome anxiety [PODCAST]

Can flu shots prevent heart attacks?

Conditions
November 4, 2025

As an internist and lipidologist, I’ve spent decades parsing data on statins, ezetimibe, PCSK9 inhibitors, and the endless parade of “LDL-lowering breakthroughs.” Yet the most potent, and perhaps the most underappreciated, intervention to prevent heart attacks each winter doesn’t come from a cardiology journal or a pharmaceutical rep. It comes from your local pharmacy fridge. For years, I’ve told my patients that getting a flu shot may prevent a heart …

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Can flu shots prevent heart attacks?

The hidden cardiovascular cost of alcohol

Conditions
November 4, 2025

A glass of wine with dinner. A cocktail on a Friday evening. A few beers over the weekend. For many of my patients, alcohol is woven seamlessly into daily life: a social lubricant, a way to unwind, even something they’ve been told might be “heart-healthy.”

Yet, in my clinic, I see the other side. A patient who comes in with fluctuating blood pressure, convinced their readings must be wrong. Another who …

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The hidden cardiovascular cost of alcohol

A cautionary tale about pramipexole

Meds
November 4, 2025

I never thought I’d be the cautionary tale.

For decades, I worked at a financial company. I’m a youth sports coach, a husband, and a father of two. I’ve spent decades coaching, mentoring players, and proudly producing high school sports telecasts. I built a life around leadership, precision, and community.

But none of that prepared me for what happened when I was prescribed pramipexole (Mirapex) to treat Parkinson’s.

The warnings were there: compulsive …

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A cautionary tale about pramipexole

What is professional inertia in medicine?

Physician
November 4, 2025

I learned that in a rural exam room where four agencies circled a child with autism; and no one moved. Not the nurse. Not the case manager. Not the system. The child failed the Autism Screening Test. He was nonverbal, avoided eye contact, even with his parents, and flapped his hands while playing with toys in unusual ways. The signs were classic. The diagnosis was clear. I spoke the “A” …

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What is professional inertia in medicine?

A Huntington’s trial brings hope and grief

Conditions
November 4, 2025

It’s been weeks since the news broke of UniQure’s trial successfully slowing the progression of HD, and I still find myself breaking down in tears. I have been going about my life, doing the groceries, going to the gym, cleaning the house, and the tears keep coming unexpectedly. I am happy about the news, but that is not how it feels in my body. I have come to realize …

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A Huntington’s trial brings hope and grief

How misinformation endangers our progress against preventable diseases [PODCAST]

Podcast
November 3, 2025
YouTube video

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Emergency physician Drew Remignanti discusses his article “A world without vaccines: What history teaches us about public health.” In this conversation, Drew reflects on historical lessons from smallpox, polio, and measles to …

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How misinformation endangers our progress against preventable diseases [PODCAST]

The rise of digital therapeutics in medicine

Physician
November 3, 2025

Most people now manage pieces of their health on a phone, from steps to sleep to blood pressure cuffs that talk to the cloud. Digital therapeutics go a step further. They are not wellness trackers or meditation apps. They are medical treatments delivered by software, built on clinical evidence, cleared by regulators, and prescribed or recommended by clinicians to prevent, manage, or treat a diagnosis. That is the core idea, …

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The rise of digital therapeutics in medicine

Lipoprotein(a): the hidden cardiovascular risk factor

Conditions
November 3, 2025

Lipoprotein(a) [Lp(a)] was, until recently, an underrecognized cardiovascular risk factor. However, extensive research over the last 15 years (including vast genome-wide association studies) has confirmed an independent, causal link between elevated lipoprotein(a) levels and atherosclerotic cardiovascular disease (ASCVD). The science has shown that, despite their small size, Lp(a) particles can have a substantial health impact, and as many as one in every five individuals worldwide has elevated levels (defined as …

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Lipoprotein(a): the hidden cardiovascular risk factor

Systematic neglect of mental health

Tech
November 3, 2025

For the third time in six weeks, a 34-year-old woman sat in an emergency room, desperate for help, and for the third time, the system failed to see her. It saw her dehydration, severe enough to require IV fluids. It saw her malnutrition, with electrolyte imbalances that required correction. It saw her vision problems, concerning enough for an ophthalmologic consultation. It saw everything except the person suffering. Each time, the …

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Systematic neglect of mental health

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