Has a highly fatal SARS coronavirus already been discovered? Maybe yes, but just its report is highly concerning. On January 4, 2024, a letter to the editor was uploaded to a preprint server which gave too few details but described a 100 percent fatal virus in genetically modified mice. The modifications made these mice similar to humans by adding a human ACE2 receptor to their cells, including in …
Topoisomerase inhibitors emerged in the American medical landscape in 1971, thanks to the discovery by Dr. Jim Wang of the E. coli omega protein. Topoisomerase I, an enzyme identified by Dr. Wang, plays a crucial role in DNA unwrapping from supercoiling. Supercoiling involves tightly wrapping DNA for storage and protection, requiring unwrapping for reading, a process in which topoisomerase is indispensable.
Topoisomerase comprises two main types, aptly named types I and …
Alaska Air Flight 1282 was on a trip from Portland to Ontario, California, on January 5, 2024. Barely six minutes into the flight, passengers heard a loud bang and a whoosh as the door plug in the middle section of the aircraft blew out. An unused exit door in the mid-part of the aircraft’s main cabin detached and fell out of the sky. One of the passengers sitting close to …
The allure of joining a startup as a health care professional is undeniable. With over 70 percent of physicians now employed by health systems and other corporate entities – we often feel like invisible cogs in a machine and feel excluded from any opportunities to contribute to real change. Social media is seemingly filled with success stories of physicians founding or joining startups and being involved in innovation, impact, and …
A recent TV advertisement attempted to recruit clients for a class action suit against a pharmaceutical manufacturer (PM) for a medication side effect (SE). The “cause of action” was unstated: was it the side effect’s existence or that the company failed to emphasize its severity?
The SE was acknowledged not only by the company but also the FDA, which nonetheless approved the medication (RX), determining that its benefits outweighed the side …
As Black History Month draws to a close, it is crucial to recognize the ongoing challenges faced by Black physicians and the importance of fostering diversity, equity, inclusion (DEI), and belonging in the medical field. National rhetoric condemning DEI efforts has made for an increasingly difficult environment for Black medical trainees to thrive. This Black History Month, we had the honor of hosting three events aimed at celebrating Black excellence …
Despite their idealized oath to do no harm, physicians are still human, and as such, mistakes, errors, and the unpredictability of life still occur. Although the stories that grab headlines are of doctors intentionally harming patients, such instances are exceedingly rare. Far more prevalent, however, are the cases of physicians who begin their careers with the best intentions, only to encounter challenges along the way. According to the American Medical …
On a fine afternoon, my nurse came in and gave me a heads-up. “Doctor, the next one’s a bit of a handful. Made a fuss scheduling, complained about her old doctor endlessly at reception … doesn’t seem like a picnic.” I smiled reassuringly, reminding her (and myself) that non-judgmental care is the cornerstone of medicine. However, my mind let out a little sigh, knowing that the next half hour was …
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Join Lyle Berkowitz, a physician executive, as we explore the challenges faced by health systems during this time, from overcrowded emergency departments to increased demand for care. Lyle shares insights into traditional strategies …
As the summer sun bids its farewell, a distinct group of people seem to “fall back” as a mysterious change begins to take hold. Several individuals get caught in the embrace of the transitions of fall and winter, revealing a shift between their mood and energy levels. Ever felt a subtle dip in energy, a touch of melancholy, or an unexpected irritability as the days grow shorter? I’m here to …
In today’s world, the term “obesity” is more than just a medical diagnosis—it’s a complex issue intertwined with personal experiences, societal norms, and systemic challenges. As a seasoned family doctor, I’ve witnessed firsthand the multifaceted nature of obesity and its profound impact on individuals’ lives. But beyond the clinical observations, I carry a personal history marked by struggles with weight and body image.
I’m a family doctor, and I have been …
March is endometriosis awareness month. Endometriosis, a disease in which tissue similar to the lining of the uterus grows outside of the uterus, affects 1 in 10 women, or 190 million individuals worldwide. Although endometriosis leads to chronic pain and fertility issues and can impact bowel, urinary, and sexual function, it may take up to 7 to 10 years after symptoms appear to be diagnosed …
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The final three minutes of my hour-long elliptical workout were not easy. Pain spread across my stomach, causing me to row in a half-sitting motion, and my chest vacillated between violent coughs and the sorts of deep breaths people take when they think they’ve seen a ghost. Perspiration fell from my shirtless torso to the garage floor. The amount of sweat was not the kind my body produces from exercise. …
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Join Kara Wada, an adult and pediatric allergy and immunology physician. We’ll delve into the world of allergy treatments, exploring the challenges faced by millions dealing with seasonal and year-round allergies. From traditional methods like …
An excerpt from Safeguarding Physician Wellbeing.
There are numerous books written by physicians of various specialties, primary care, and subspecialists, on the topic of physician burnout. Most physician authors, like me, have been inspired to write a book due to personal experience with a high degree of burnout, and/or have had academic interests and research on the topic. Writing such books can be cathartic, intended as a warning for our …
Patients come into the emergency department (ED) with symptoms, not diagnoses. That’s when time is of the essence. Clinicians must quickly triage patients and establish an appropriate care pathway to obtain the best possible outcome. Most patients entering the ED are time-sensitive, requiring clear protocols for care. However, even some of the deadliest conditions still lack the necessary data, tools, and standards to quickly diagnose and effectively treat patients.
Over the …
I had a teacher in my third year of med school. His name was Dr. T. He taught us pediatrics. At that time, he was the head of the department of pediatrics in the busiest teaching hospital in our city, where I was working. Every day, hundreds of children from far-flung areas are referred to our hospital with complications due to suboptimal treatment received in their local areas, as we …
I am a former associate director in a state physician health program (PHP). I also hold faculty appointments at Baylor College of Medicine and Harvard Medical School in medical ethics and psychiatry.
There is a little-known nether realm inhabited by a subset of doctors who have or are suspected of having substance use disorders. These physicians often are referred to state PHPs which, because they’re generally considered voluntary in nature, have …
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