In a major advance in medicine, a man with type 1 diabetes is making his own insulin again, this time using genetically engineered donor islet cells. Researchers provided the new cells with an invisibility cloak to allow them to escape immune detection. After three months of follow-up, his body had not only accepted the new tissue but was quietly producing insulin. This single-patient proof-of-concept study gives hope to the millions …
A recent Washington Post article called for earlier detection of atherosclerosis and a shift from “ischemia-centric” thinking to an “atheroma-centric” model. That’s progress, but it’s still missing the most important piece: Plaque isn’t the root cause.
For 50 years, we’ve built a trillion-dollar cardiology machine around the cholesterol hypothesis. Statins, PCSK9 inhibitors, ezetimibe, inclisiran, Lp(a) drugs, all circling the same biochemical drain. LDL plays a role, yes. But LDL is …
HBO’s The Pitt collected thirteen Primetime Emmy nominations this year, winning both Outstanding Drama Series and Outstanding Lead Actor in a Drama Series for Noah Wyle. But the recognition was not just for great television. The series struck a cultural nerve because it captured something raw and real: the emotional side of medicine. Viewers saw the chaos of an emergency room after a mass casualty event, the head physician …
As a research scientist who is devoted to ensuring that immigrant nurses have successful U.S. careers, the issue of internationally educated nurses’ (IENs’) cross-culture language competence has recently been both a sensitive and front-and-center issue pervading my work. In my more than 30 years in the health care sphere, the topic is now reaching a fever-pitch as IENs increasingly enter the U.S. health care workforce and play a critical role …
At age 81, I speak and write voluminously as a health care educator specializing in public health policy and practice for the treatment of pain and addiction. My wife and I are also careful about getting our periodic vaccinations for flu and COVID-19. A few days ago we responded to an invitation from our pharmacy to drop in for our shots on a walk-in basis. The process turned out to …
The pandemic changed us in ways that cannot be measured by infection rates alone. Beyond the physical toll, it left lasting scars on our mental health. Fear, uncertainty, and isolation became daily realities. As a health professional and researcher, I wanted to understand how people could begin to heal. During my doctoral work, I studied adults who engaged in different wellness practices after the pandemic. Some found relief in nature: …
When I tell colleagues that I offer Valtrex (valacyclovir) and low-dose lithium orotate to patients worried about developing Alzheimer’s, the silence in the room thickens. Someone always asks, “Where’s the randomized controlled trial?” That’s exactly the problem. We keep waiting for perfect evidence while the disease eats away at people’s brains.
I’m an internist and lipidologist who’s spent years watching the medical establishment chase the wrong villains, like cholesterol, salt, …
When the FOURIER trial was published in 2017, cardiologists and lipidologists everywhere hailed it as proof that lowering LDL with PCSK9 inhibitors “saves lives.” But when you actually read the data, not the press releases, it’s hard not to shake your head.
Over a median of 2.2 years, evolocumab (Repatha) reduced nonfatal heart attacks by about 0.9 percent and had no significant impact on death. The absolute risk reduction for all-cause …
While work-related stress continues to be a major cause of burnout, new research shows that non-work stressors like caregiving demands, financial instability, and personal life conflicts also greatly increase the risk. Yet, the dominant narrative has not caught up, and many still believe burnout is only a workplace problem, overlooking the deeper, life-wide imbalance it often reflects.
Recently, I spoke to a nurse on sick leave for the third time …
Jodie Green and I have been following each other on social media for a couple of years, and we finally had a conversation a few months ago. We discussed our appreciation for the work each of us is doing to support doctors and all other health care professionals, including my efforts and Jodie’s with her organization, the Clinician Burnout Foundation. We’re amplifying meaningful resources that are available for …
For decades, I treated patients with chronic pain. One truth became evident early: most older adults prescribed narcotics use them responsibly. My clinical acumen, shaped over more than forty years, intuitively knew this to be true. Still, I understood that intuition and opinion alone are insufficient. Compassion in medicine must be paired with objectivity.
Now the data confirms what practice long suggested. A national survey of adults aged 50 and older …
An 18-year-old was admitted to our ICU with a questionable diagnosis. The drug screen did not reveal what he had taken. Our ICU intensivist speculated he ingested bath salts. Bath salts came to the U.S. around the 2010s. It was cheap and, even better, considered a “legal high” as it was not detectable in drug tests. Josh came to the emergency room psychotic, paranoid, and hallucinating, with hypertension and SVT. …
The names read like a roll call of Black excellence: congressman John Lewis, the civil rights icon who walked across the Edmund Pettus Bridge and helped change America; congresswoman Sheila Jackson Lee, the tireless advocate for justice who represented Houston for nearly three decades; Aretha Franklin, the Queen of Soul whose voice defined generations; reverend Dr. Calvin O. Butts III, the prophetic voice from Abyssinian Baptist Church who fought for …
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Many people have become “burned out” on the word burnout. Many doctors do not resonate with the term, feeling it describes personal struggles, when systemic issues are the root cause of the challenges facing health care professionals. They offer “moral injury” as a more accurate description. Clinicians can experience either or both at any time during their career.
Recently speaking with Shari Morin-Degel, I appreciated her sharing that because she had …
SGLT2 inhibitors have transformed care for people with type 2 diabetes. They not only lower blood sugar but also reduce cardiovascular events and slow the progression of kidney disease. Given these successes, many have asked whether the same benefits extend to people with type 1 diabetes (T1D).
The answer is not straightforward. In T1D, SGLT2 inhibitors remain off-label, and the biggest concern is the increased risk of diabetic ketoacidosis (DKA). Still, …
A brilliant, like-minded cardiologist recently shared with me “A Reappraisal of the Lipid Hypothesis” by Dr. Robert DuBroff, published in The American Journal of Medicine. It should be required reading for every physician who has ever written “continue statin” without a second thought.
DuBroff’s analysis reviewed 29 randomized controlled trials of cholesterol-lowering therapy conducted after modern trial regulations were adopted. The results were quietly devastating:
An excerpt from How I Know White People Are Crazy and Other Stories. Copyright © 2025 Dr. Jonathan Lassiter. Published by Legacy Lit, a Hachette Book Group company. Reproduced by arrangement with the publisher. All rights reserved.
According to Dr. James M. Stedman, a white male clinical psychologist from the University of Texas Health Science Center at San Antonio, there was a shortage of [doctoral] internships as early as 1976. …
In inpatient psychiatry, teams often face a familiar problem: The clinicians at the bedside see ongoing risk that warrants hospital-level care, while the payer’s reviewer concludes the stay is no longer “medically necessary.” The result can be frustration, rushed discharges, or days spent on the phone. Behind the scenes, costs mount; measured not just in dollars, but in readmissions, emergency department boarding, and clinician burnout. Physician advisors help resolve this …
Is your baby’s safe sleep a privilege?
In my Bronx clinic, I often sit across from new families who are well-versed in the American Academy of Pediatrics’ (AAP) safe sleep guidelines. Babies should sleep alone, on their backs, in a crib free of soft bedding and toys. Yet despite this knowledge, many parents, especially those who choose to exclusively breastfeed, face real-life barriers in following these recommendations. For single mothers and …
John, a man in his early sixties, waited nine months to see me about memory problems. When he finally arrived, I had twenty minutes. Eighteen went to detective work, extracting fragments of history from conflicting accounts, piecing together months of decline from unreliable memories, and completing a paper-based subjective memory test. What should have been a full consultation of patient-focused care, was reduced to only a few hurried minutes at …
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